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The endogenous phospholipid l-alpha-lysophosphatidylinositol (LPI) was recently identified as a novel ligand for the orphan G protein-coupled receptor 55 (GPR55). In this study we define theContinue Reading
  • Markus Waldeck-Weiermair, Cristina Zoratti, +5 authors Wolfgang F. Graier
  • Biology, Medicine
  • Journal of cell science
  • 2008 (First Publication: 15 May 2008)
  • Although the endocannabinoid anandamide is frequently described to act predominantly in the cardiovascular system, the molecular mechanisms of its signaling remained unclear. In human endothelialContinue Reading
  • Christopher M. Henstridge, Nariman A. B. Balenga, +9 authors Andrew James McGregor Irving
  • Chemistry, Medicine, Biology
  • British journal of pharmacology
  • 2010 (First Publication: 1 June 2010)
  • BACKGROUND AND PURPOSE Although GPR55 is potently activated by the endogenous lysophospholipid, L-alpha-lysophosphatidylinositol (LPI), it is also thought to be sensitive to a number of cannabinoidContinue Reading
  • Julia Kargl, Andrew J. Brown, +4 authors Akos Heinemann
  • Medicine, Chemistry
  • The Journal of pharmacology and experimental…
  • 2013 (First Publication: 1 July 2013)
  • The G protein-coupled receptor 55 (GPR55) is a lysophosphatidylinositol (LPI) receptor that is also responsive to certain cannabinoids. Although GPR55 has been implicated in severalContinue Reading