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Macroscopic Cellular Automata characterize a methodologi-cal approach for modelling large scale (extended for kilometres) complex acentric phenomena, e.g. surface flows as lava flows, debris flows etc.. This paper concerns the extension of such a method in order to simulate combined subaerial-subaqueous flow-like landslides. The occurrence of heterogeneous(More)
The coordinate modulation of cadherin and integrin functions plays an essential role in fundamental physiological and pathological processes, including morphogenesis and cancer. However, the molecular mechanisms underlying the functional crosstalk between cadherins and integrins are still elusive. Here, we demonstrate that the small GTPase Rap1, a crucial(More)
BACKGROUND The aim of this study is to investigate the association between social relationships and Health Related Quality of Life (HRQL) among the elderly in Italy. METHODS A sample of 33,744 Italian residents, representing the non-institutionalised population aged 60 years and over was extracted from the national ISTAT cross-sectional survey during(More)
Cellular Automata (CA) represent an alternative approach to differential equations to model and simulate complex fluid dynamical systems, whose evolution depends on the local interactions of their constituent parts. A new notion of CA was developed by our research group Empedocles. It permitted to improve significantly an empirical method for modelling(More)
This paper presents the latest developments of the deterministic Macroscopic Cellular Automata model SCIARA for simulating lava flows. A Bingham-like rheology has been introduced for the first time as part of the Minimization Algorithm of the Differences, which is applied for computing lava outflows from the generic cell towards its neighbours. The(More)
The coordinate modulation of the cellular functions of cadherins and integrins plays an essential role in fundamental physiological and pathological processes, including morphogenesis, tissue differentiation and renewal, wound healing, immune surveillance, inflammatory response, tumour progression, and metastasis. However, the molecular mechanisms(More)
When an health condition has been identified, the question of whether to continue driving depends not on a medical diagnosis, but on the functional consequences of the illness. The complex nature of physical and mental impairments and their relationship with safe driving make the availability of evidence based tools necessary for health professionals. The(More)