Maria Vittoria Avolio

Learn More
The coordinate modulation of cadherin and integrin functions plays an essential role in fundamental physiological and pathological processes, including morphogenesis and cancer. However, the molecular mechanisms underlying the functional crosstalk between cadherins and integrins are still elusive. Here, we demonstrate that the small GTPase Rap1, a crucial(More)
BACKGROUND The aim of this study is to investigate the association between social relationships and Health Related Quality of Life (HRQL) among the elderly in Italy. METHODS A sample of 33,744 Italian residents, representing the non-institutionalised population aged 60 years and over was extracted from the national ISTAT cross-sectional survey during(More)
The coordinate modulation of the cellular functions of cadherins and integrins plays an essential role in fundamental physiological and pathological processes, including morphogenesis, tissue differentiation and renewal, wound healing, immune surveillance, inflammatory response, tumour progression, and metastasis. However, the molecular mechanisms(More)
Macroscopic Cellular Automata characterize a methodological approach for modelling large scale (extended for kilometres) complex acentric phenomena, e.g. surface flows as lava flows, debris flows etc.. This paper concerns the extension of such a method in order to simulate combined subaerial-subaqueous flow-like landslides. The occurrence of heterogeneous(More)
Cellular Automata (CA) represent an alternative approach to differential equations to model and simulate complex fluid dynamical systems, whose evolution depends on the local interactions of their constituent parts. A new notion of CA was developed by our research group Empedocles. It permitted to improve significantly an empirical method for modelling(More)
Cerebral cavernous malformations (CCM) are vascular malformations, mostly located in the central nervous system, which occur in 0.1-0.5% of the population. They are characterized by abnormally enlarged and often leaking capillary cavities without intervening neural parenchyma. Some are clinically silent, whereas others cause seizures, intracerebral(More)