Maria Teresa La Rovere

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As the atrial baroreflex importantly contributes to modulation of the autonomic influences on the heart and thereby arrhythmogenesis, baroreflex sensitivity has been used as a measure of the interaction between sympathetic and parasympathetic activities at the cardiac level. The most widely applied technique both in the experimental and clinical setting is(More)
Portable polysomnography (PSG) and cardiorespiratory polygraphy are increasingly being used in the assessment of sleep-disordered breathing (SDB) in heart failure patients. Scoring of SDB from cardiorespiratory polygraphy recordings is based only on respiratory signals, while electroencephalographic, electrooculographic and electromyographic channels are(More)
Portable sleep apnea monitors are often used to screen for sleep-disordered breathing in chronic heart failure patients (CHF), but night-to-night repeatability of obtained measurements of nocturnal breathing disorders has not been fully assessed. Fifty-six stable, moderate-to-severe CHF patients [male, 87%; age, 57 ± 9 years; NYHA class, 2.6 ± 0.6; left(More)
In this paper, we describe a computer program (RESP-24) specifically devised to assess the prevalence and characteristics of breathing disorders in ambulant chronic heart failure patients during the overall 24 h period. The system works on a single channel respiratory signal (RS) recorded through a Holter-like portable device. In the pre-processing stage(More)
Higher neurohormonal activation levels are known markers of severity in heart failure (HF). Aim of the study was to assess the association of Poincarè plot indexes (PPI) of RR time series with plasma norepinephrine (NPE) levels and functional parameters as compared to classical linear indexes of HRV. Ninety-nine HF patients underwent to a 24-hour(More)
The aim of this study was to compare the pharmacokinetics and antiarrhythmic activity of dihydroquinidine and quinidine in 14 patients (11 men, 3 women, aged 28 to 67 years) with heart disease and chronic, stable, highfrequency premature ventricular beats (PVB) (>100/hr). A randomized, double-blind, crossover, placebo-controlled protocol was utilized.(More)
The physiological mechanisms responsible for periodic breathing (PB) in heart failure (HF) patients are still debated. A role for rhythmic shifts in the level of wakefulness has been suggested, but their existence has never been proven. In this study we investigated the existence of an oscillation in EEG activity during PB in these patients and assessed its(More)
A periodic breathing (PB) pattern is often observed in chronic heart failure (CHF) patients (pts). In order to clarify the role of this abnormal respiratory activity upon heart period variability we investigated, in a group of 20 stable CHF pts (NYHA class II to III, median EF 24%) showing a PB pattern, 1) whether observed data were consistent with the(More)
In this study we appraised three new criteria for the computation of baroreflex sensitivity (BRS) using the transfer function magnitude (TFM) method, with the aim of overcoming the conventional requirement of a coherence ≥ ≥ ≥ ≥ 0.5 between arterial pressure and RR interval time series. Measurements were carried out in a sample of 44 post-myocardial(More)