Maria Teresa Alvarez-Martinez

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Prion diseases are characterized by the accumulation in the central nervous system of an abnormally folded isoform of the prion protein, named PrPSc. Aggregation of PrPSc into oligomers and fibrils is critically involved in the pathogenesis of prion diseases. Oligomers are supposed to be the key neurotoxic agents in prion disease, so modulation of prion(More)
In a previous work by Alvarez-Martinez et al. (2011), the authors pointed out some fallacies in the mainstream interpretation of the prion amyloid formation. It appeared necessary to propose an original hypothesis able to reconcile the in vitro data with the predictions of a mathematical model describing the problem. Here, a model is developed accordingly(More)
Theoretically speaking, heavy tax rates on gambling should dampen growth of the casino revenues. Indeed, a cursory glance at data across U.S. states suggests more jobs and income are generated directly by the gaming industry when lower tax rates are applied. Using a detailed computable general equilibrium model, we evaluate the effects of a proposed(More)
(8/94-6/01) Investigating (with Hayian Zhang) causes of the great change in China's energy intensity from 1997 to present with some comparisons to the happenings in the United States. Estimating the economic impacts of catastrophic damage to key transit infrastructure to a metropolitan economy via a computable general equilibrium model of New Jersey and(More)
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