• Publications
  • Influence
Nutritional evaluation and bioactive microconstituents (phytosterols, tocopherols, polyphenols, triterpenic acids) in cooked dry legumes usually consumed in the Mediterranean countries.
Abstract In the present study we report the crude composition and several bioactive microconstituents content in cooked dry legumes, usually consumed in Mediterranean countries. The legumes studiedExpand
  • 177
  • 9
Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors*
Nerve growth factor (NGF) is produced as a precursor called pro-nerve growth factor (proNGF), which is secreted by many tissues and is the predominant form of NGF in the central nervous system. InExpand
  • 98
  • 7
Rab35: GEFs, GAPs and effectors.
Rabs are the largest family of small GTPases and are master regulators of membrane trafficking. Following activation by guanine-nucleotide exchange factors (GEFs), each Rab binds a specific set ofExpand
  • 84
  • 5
DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior
The small guanosine triphosphatase Rab13 functions in exocytic vesicle trafficking in epithelial cells. Alterations in Rab13 activity have been observed in human cancers, yet the mechanism of Rab13Expand
  • 54
  • 5
Retention and distribution of natural antioxidants (α-tocopherol, polyphenols and terpenic acids) after shallow frying of vegetables in virgin olive oil
Potatoes, green peppers, zucchinis and eggplants were shallow fried in virgin olive oil (VOO) according to the Mediterranean traditional culinary practice. Zucchinis and eggplants were also blanketedExpand
  • 58
  • 4
Recovery and distribution of natural antioxidants (α-tocopherol, polyphenols and terpenic acids) after pan-frying of Mediterranean finfish in virgin olive oil
Abstract Samples of eight finfish representing the most popular fish species in Greece were pan-fried in virgin olive oil according to the Greek traditional culinary practice. Analyses forExpand
  • 65
  • 3
Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity
Metabolic coordination between neurons and astrocytes is critical for the health of the brain. However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural activity,Expand
  • 45
  • 3
Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton
Connecdenn 3, a member of the connecdenn/DENND1 family of DENN domain–containing guanine-nucleotide exchange factors for Rab35, is demonstrated to bind directly to actin and specifically activatesExpand
  • 31
  • 2
Scyl1 scaffolds class II Arfs to specific subcomplexes of coatomer through the &ggr;-COP appendage domain
ABSTRACT Coatomer (COPI)-coated vesicles mediate membrane trafficking in the early secretory pathway. There are at least three subclasses of COPI coats and two classes of Arf GTPases that couple COPIExpand
  • 26
  • 2
Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors*
Background: Connecdenns are GEFs for Rab35, a GTPase controlling endocytic recycling. Regulation of connecdenn function is unknown. Results: The GEF activity of connecdenn 1 and 2 are autoinhibited,Expand
  • 10
  • 2