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OBJECTIVE Patients with early multiple sclerosis (MS) have stereotyped attack severity and recovery. We sought to determine if polymorphisms in MS susceptibility genes are associated with these attack features or with the risk of a second attack. METHODS 503 white subjects evaluated within a year of MS onset were included in the study. The severity of and(More)
OBJECTIVE The anatomic location of subsequent relapses in early multiple sclerosis (MS) appears to be predicted by the first attack location. We sought to determine if genetic polymorphisms associated with MS susceptibility are associated with attack location. METHODS 17 genome-wide association study-identified MS susceptibility polymorphisms were(More)
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