Maria Polakowska

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The prevalence of the familial defective apolipoprotein B-100 (FDB) Arg3500Gln mutation in 525 unrelated hypercholesterolaemic Polish subjects was evaluated. DNA samples were screened for FDB mutation using SSCP method. Presence of mutation was confirmed using a mismatch MspI PCR strategy. Plasma lipid levels and clinical characteristics of 13 patients(More)
INTRODUCTION Incidence of diabetes is increasing at an alarming rate worldwide. It has been estimated that 2.2 to 2.5 million of Poles will be affected by this disease by 2030. OBJECTIVES The aim of the study was to conduct an epidemiological analysis of the incidence of diabetes and impaired fasting glucose (IFG) in the Polish population. PATIENTS AND(More)
Two sources of information about deaths caused by myocardial infarction and stroke were compared: official statistical data obtained from the Central Statistical office (CSO), and data from the registers of myocardial infarction and stroke conducted under the POL-MONICA Warsaw Project. The completeness of the MONICA registers with respect to the CSO data(More)
BACKGROUND AND PURPOSE Stroke mortality has decreased in most industrialized countries in recent decades. In Poland, as in other eastern European countries, mortality rates for stroke remain high. METHODS The Warsaw Stroke Registry (WSR) registered patients in the Mokotów district of Warsaw from 1991 through 1992. The Warsaw Pol-MONICA study registered(More)
There is considerable interest in the association of snoring and health consequences that have been linked to more severe sleep-disordered breathing, including obstructive sleep apnoea syndrome. The goal of this investigation was to assess the independent association of heavy, habitual snoring and daytime sleepiness. For this, a cross-sectional, population(More)
Hyperhomocysteinemia has been recognised as an independent risk factor for cardiovascular, cerebrovascular and peripheral artery disease. There is strong evidence suggesting that hyperhomocysteinemia accelerates the process of atherogenesis. Possible explanations for this will be shortly reviewed. Recently a growing interest has been focused on the(More)
BACKGROUND During the last decade, the beneficial changes in lifestyle and in medical care increased average life expectancy, particularly in patients with chronic diseases such as hypertension and coronary heart disease. Unfortunately this also increased the number of patients, particularly among the elderly, who are susceptible to complications of these(More)
The present study, based on the World Health Organization (WHO) MONICA Project design, covers two Warsaw districts inhabited by 274442 people, aged 25-64. In the studied population over the years 1976-1985, no significant time-trends were found of cardiovascular disease (CVD), ischemic heart disease (IHD), myocardial infarction (MI) and cerebrovascular(More)