Maria Magdalena Coman

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Conserved residues in the d subunit help the E. coli clamp loader, c complex, target primer-template DNA for clamp assembly ABSTRACT The Escherichia coli clamp loader, c complex (c 3 dd'kc), catalyzes ATP-driven assembly of b clamps onto primer-template DNA (p/tDNA), enabling processive replication. The mechanism by which c complex targets p/tDNA for clamp(More)
The CD8 co-receptor influences T cell recognition and responses in both anti-tumor and anti-viral immunity. During evolution in the ancestor of humans and chimpanzees, the CD8B gene acquired two additional exons. As a result, in humans, there are four CD8β splice variants (M1 to M4) that differ in their cytoplasmic tails. The M-1 isoform which is the(More)
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