Maria Müller

Bernd Zechmann7
Werner Kühlbrandt2
Ernst Bamberg2
Christian Bamann2
7Bernd Zechmann
2Werner Kühlbrandt
2Ernst Bamberg
2Christian Bamann
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Channelrhodopsin-2 (ChR2) is the prototype of a new class of light-gated ion channels that is finding widespread applications in optogenetics and biomedical research. We present a 6-Å projection map of ChR2, obtained by cryo-electron microscopy of two-dimensional crystals grown from pure, heterologously expressed protein. The map shows that ChR2 is the same(More)
This study describes the subcellular distribution of glutathione in roots and leaves of different plant species (Arabidopsis, Cucurbita, and Nicotiana). Glutathione is an important antioxidant and redox buffer which is involved in many metabolic processes including plant defense. Thus information on the subcellular distribution in these model plants(More)
Plants cope with cadmium (Cd) stress by complexation with phytochelatins (Pc), metallothioneins and glutathione and sequestration within vacuoles. Especially glutathione was found to play a major role in Cd detoxification as Cd shows a high binding affinity towards thiols and as glutathione is a precursor for Pc synthesis. In the present study, we have used(More)
Compartment specific changes in ascorbate and glutathione contents were studied during drought stress in Arabidopsis thaliana Col-0 and in ascorbate and glutathione deficient mutants vtc2-1 and pad2-1, respectively, over a time period of 10 days. The results of this study revealed a strong decrease of glutathione contents in both mutants (up to 52% in(More)
Excess light conditions induce the generation of reactive oxygen species (ROS) directly in the chloroplasts but also cause an accumulation and production of ROS in peroxisomes, cytosol and vacuoles. Antioxidants such as ascorbate and glutathione occur in all cell compartments where they detoxify ROS. In this study compartment specific changes in antioxidant(More)
Sufficient sulfate supply has been linked to the development of sulfur induced resistance or sulfur enhanced defense (SIR/SED) in plants. In this study we investigated the effects of sulfate (S) supply on the response of genetically resistant tobacco (Nicotiana tabacum cv. Samsun NN) to Tobacco mosaic virus (TMV). Plants grown with sufficient sulfate (+S(More)
Channelrhodopsin-2 (ChR2) is a cation-selective light-gated channel from Chlamydomonas reinhardtii (Nagel G, Szellas T, Huhn W, Kateriya S, Adeishvili N, Berthold P, et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci USA 2003;100:13940-5), which has become a powerful tool in optogenetics. Two-dimensional(More)
  • Vassilis F. Siyiannis, Vassilis E. Protonotarios, Bernd Zechmann, Styliani N. Chorianopoulou, Maria Müller, Malcolm J. Hawkesford +1 other
  • 2011
Nitrate (N), phosphate (P) or sulphate (S) deprivation causes aerenchyma formation in maize (Zea mays L.) nodal roots. The exact mechanisms that trigger the formation of aerenchyma under these circumstances are unclear. We have compared aerenchyma distribution across the nodal roots of first whorl (just emerging in 10-day-old seedlings), which were subject(More)
Massive Open Online Courses (MOOCs), insbesondere die instruktions-orientierten xMOOCs, werden häufig auf speziell dafür entwickelten Plattformen, wie Coursera, edX oder iversity durchgeführt. Nachdem deutsche Hochschulen in den letzten Jahren in Lernmanagementsysteme (LMS) investiert haben, liegt es na-he, deren Tauglichkeit für die Realisierung der neuen(More)