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Design and synthesis of new trehalose‐conjugated pentapeptides as inhibitors of Aβ(1–42) fibrillogenesis and toxicity
- Paolo de Bona, Maria Laura Giuffrida, +6 authors E. Rizzarelli
- Chemistry, Medicine
- Journal of peptide science : an official…
- 1 March 2009
Three new trehalose‐conjugated peptides of the well known β‐sheet breaker peptide iAβ5p, were synthesized and tested as inhibitors of Aβ toxicity toward pure cultures of rat cortical neurons. Expand