Maria Jesús Martinez de Osaba

Learn More
BACKGROUND Precise calcium (Ca) and vitamin D intestinal absorption after gastric bypass (GB) remains unknown. We evaluated the effect of receiving or not Ca and vitamin D supplementation on Ca, PTH, and vitamin D axis in patients undergoing GB. METHODS Two hundred twenty-two patients were evaluated prior to GB and at 1 year. Baseline characteristics were(More)
The influence of osteoprotegerin and RANKL as regulators of osteoclastogenesis and bone remodeling in liver disease and in the development of osteoporosis in primary biliary cirrhosis (PBC) is uncertain. Therefore, 68 women with PBC and 20 healthy females were studied by assessing circulating osteoprotegerin and RANKL. Bone mineral density and markers of(More)
Cortisol-binding globulin (CBG) is an alpha-1-glycoprotein with high affinity for cortiso that could be a potential biological marker of chronic stress, according to several previous studies. In order to examine CBG concentrations in bipolar disorder, we determined serum CBG levels by radioimmunoassay with monoclonal antibodies in a sample of 39 RDC bipolar(More)
The aim of this study was to analyse the clinical manifestations and the most frequent causes of osteomalacia (OM) in a group of 28 patients diagnosed with this disorder during a 20-year period. OM was diagnosed by bone biopsy and/or by Bingham and Fitzpatrick criteria (two of the following: low calcium, low phosphate, elevated total alkaline phosphatase(More)
Serotonin (5-HT)1A autoreceptors are involved in regulating 5-HT cell firing and were implicated in depression (Blier and de Montigny 1994; Cowen 2000). The sensitivity of 5-HT1A receptors in humans can be measured using the technique of pharmacological challenge (Cowen 2000). In normal subjects, 5-HT1A receptor agonists such as buspirone, ipsapirone, or(More)
  • 1