Maria Isabel Rojo

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Introduction Urticaria and angioedema lasting more than 6 weeks have been designated as chronic urticaria (CU). It encompasses two major subtypes: chronic spontaneous urticaria (CSU) (previously known as chronic idiopathic urticaria) (CIU) and chronic inducible urticaria. CSU has been defined as wheals and/or angioedema that are endogenous and independent(More)
A close relationship between histone synthesis and DNA replication has been suggested for many biological systems. The presence of histonic proteins has been demonstrated in practically all kinds of eukaryotic cells. During the clevage period of sea urchins it has been postulated that histones are not present in nuclei, and that only at blastula stage they(More)
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