Maria Imaculada Muniz-Junqueira

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UNLABELLED Phagocytosis by neutrophils and monocytes constitutes the main defense mechanism against bacterial challenges in periodontitis. Phagocytosis by neutrophils has already been evaluated, whereas phagocytic function of monocytes has hardly been addressed so far. OBJECTIVES The aim of this study was to assess phagocytosis by neutrophils and(More)
BACKGROUND Corticosteroids are the first-line therapy for asthma; however, the effect of corticosteroids on the innate immune system remains unclear. This study's objective was to evaluate the effect of inhaled corticosteroid therapy (ICT) on phagocytic functions. METHODS To evaluate the impact of ICT, the phagocytosis of Saccharomyces cerevisiae by blood(More)
BACKGROUND Early identification of the severity of asthma exacerbation would be helpful for the management of patients. We aimed to evaluate the correlation of morphological change in activated eosinophils and the severity of an asthma exacerbation. METHODS Blood was collected from 55 asthmatic children: 40 of whom were having an exacerbation, 15(More)
BACKGROUND There is no consensus on the mechanisms by which anti-cyclic citrullinated peptide antibodies (anti-CCP) and rheumatoid factor (RF) influence the pathogenesis of rheumatoid arthritis (RA). The current study verified if the presence of RF or anti-CCP is associated with phagocytic capacity and reactive oxygen species (ROS) production by phagocytes(More)
1.31) were randomized to 1 of the 4 treatment groups. MF/F increased the time to first asthma deterioration thus decreasing the proportion of subjects experiencing asthma deterioration during the study (MF/F ¼ Low rates of AEs were observed and were similar between treatment arms. Conclusions: In asthmatics previously treated with low-dose ICS with or(More)
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