Alpha-synuclein, the major component of Lewy bodies, is thought to play a central role in the onset of synaptic dysfunctions in Parkinson's disease (PD). In particular, α-synuclein may affect dopaminergic neuron function as it interacts with a key protein modulating dopamine (DA) content at the synapse: the DA transporter (DAT). Indeed, recent evidence from… (More)
The real-time detection and tracking of moving objects is a challenging task and automatic tools to identify and follow them are often subject to constraints regarding the environment under investigation or the full visibility of the targeted object. Exploiting the possibility of a multi-source acquisition in the targeted scene, firstly detection is… (More)
A research has been carried out finalised to the definition of a methodology useful to address the task of detection and tracking of moving targets. Algorithms performing this task for real time monitoring and surveillance purposes have been developed. Due to deformations occurring in the appearance of the target in real time video sequences, a Hierarchical… (More)
In addressing classification, there are two issues: a) class discovery, the definition of previously unrecognized tissue sub-types, and b) class prediction, the assignment of particular samples to existing classes (this could reflect current states or even future outcomes). The main challenge of the Prognochip prospective study is the development of… (More)
Access to the published version may require subscription. Tavole 241 Abstract Several films by Woody Allen (Interiors, Oedipus Wrecks, Match Point and Mighty Aph-rodite) contain elements of classical tradition that have been neglected or oversimplified by film scholarship as references to the director's personal engagement with psychoanalysis. Using Mighty… (More)
reference-channel based methodology to improve estimation of event-related hemodynamic response from fNIRS measurements. (2012). When time is space: Evidence for a mental time line. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. vol.; p.- .
To my family v Acknowledgments I would like to express my sincere gratitude to Prof. Fulvio Gini and Dr. Alfonso Farina for their precious suggestions and for the great work environment that they have created during the development of this research project. Integrati, Roma, Italy, for their help and for their comments since the beginning of this activity. I… (More)