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OBJECTIVE To investigate putative changes in cortical excitability of patients affected by early-onset mild dementia by means of transcranial magnetic stimulation (TMS) and to verify whether a peculiar neurophysiological profile may contribute to characterise Alzheimer's disease (AD) vs frontotemporal dementia (FTD). METHODS Motor threshold and(More)
Electroencephalograph (EEG)-based brain-computer interfaces (BCI's) require on-line detection of mental states from spontaneous EEG signals. In this framework, surface Laplacian (SL) transformation of EEG signals has proved to improve the recognition scores of imagined motor activity. The results we obtained in the first year of an European project named(More)
In this work, a novel approach based on the estimate of time-varying graph indices is proposed in order to capture the basic schemes of communication within the functional brain networks during a simple motor act. To achieve this, we used a cascade of computational tools able to estimate first the electrical activity of the cortical surface by using(More)
–This paper presents first results of an Adaptive Brain Interface suitable for deployment outside controlled laboratory settings. It robustly recognizes three purely mental states from on-line spontaneous EEG signals and has them associated to simple commands. Three commands allow to interact intelligently with a computer-based system through task(More)
Obstructive sleep apnea (OSA) is accompanied by neurocognitive impairment, likely mediated by injury to various brain regions. We evaluated brain morphological changes in patients with OSA and their relationship to neuropsychological and oximetric data. Sixteen patients affected by moderate-severe OSA (age: 55.8±6.7 years, 13 males) and fourteen control(More)
The opening of a communication channel between brain and computer [brain-computer interface (BCI)] is possible by using changes in electroencephalogram (EEG) power spectra related to the imagination of movements. In this paper, we present results obtained by recording EEG during an upper limb motor imagery task in a total of 18 subjects by using(More)
Until now, in EEG studies the activity of the brain during simple or complex tasks have been recorded in a single subject. Often, during such EEG recordings, subjects interacts with the external devices or the researchers in order to reproduce conditions similar to the those usually occurring in the real-life. However, in order to study the concurrent(More)
OBJECTIVE To investigate whether repetitive transcranial magnetic stimulation (rTMS) can modify spasticity. METHODS We used high-frequency (5 Hz) and low-frequency (1 Hz) rTMS protocols in 19 remitting patients with relapsing-remitting multiple sclerosis and lower limb spasticity. RESULTS A single session of 1 Hz rTMS over the leg primary motor cortex(More)
The present work aims at analyzing the structure of cortical connectivity during the attempt to move a paralyzed limb by a group of spinal cord injured (SCI) patients. Connectivity patterns were obtained by means of the Directed Transfer Function applied to the cortical signals estimated from high resolution EEG recordings. Electrical activity were(More)