Maria Gołębiowska-Wawrzyniak

Learn More
UNLABELLED The causes of osteosarcoma (OS) and effector mechanisms of the immune response against OS and other neoplastic diseases remain unknown. According to current knowledge, the major role is attributed to cytotoxic T lymphocytes, NK, NKT and Tăä lymphocytes, which are engaged directly in the destruction of the tumour cells. Helper T lymphocytes (CD4+)(More)
BACKGROUND As the frequency of allergic disease and especially the food allergy in children is still increasing - we undertook studies to determine the specific sensitivity of lymphocytes T in order to improve the diagnostics and monitoring of treatment. The usefulness of evaluation CD69 and PCNA expression of T cells from children with cow's milk allergy(More)
Many studies in vitro and in vivo have shown immunomodulating and antiviral activities of inosine pranobex. The object of this research was to examine the potential beneficial effects of inosine pranobex (Groprinosin) on immune system in children with cellular immunodeficiency as a prophylaxis of recurrent infections, mainly of viral origin. 50 mg/kg(More)
UNLABELLED THE AIM of this study was to evaluate selected parameters of calcium and phosphorus metabolism in children with CMA treated with the following milk substitute formulas: lactose-containing extensively hydrolyzed wheat protein formula, lactose-free extensively hydrolyzed casein protein formula, as well as soy-based formula. MATERIAL AND METHODS(More)
BACKGROUND Osteosarcoma (OS) is the most frequent primary malignant bone tumour, mainly affecting children in the first and second decade of life. Causes of the disease are still unknown and reaction of the immune system on its development is very individual. Particular emphasis must be placed on the role of cytokines in the immunoregulatory and(More)
therapy on the basis of the immunodeficiency, with evident improvement , 1 did not received and had some improvement of their symptoms. Conclusions: We found out that the 8 patients with autoimmunity had allergy and also mixed T and B immunodeficiency. We conclude that the physicians should be aware of the correlation in chronic inflammation and the(More)
including potatoes, bananas and vegetables all tested positive in 4% of the children. Pumpkin tested positive in one infant who had presented with rectal bleeding. Majority of the children had positive tests to multiple foods. Only 14% of the children had negative tests. The commonest gastrointestinal (GI) symptoms were abdominal pain (38%), constipation(More)
BACKGROUND Food allergy is an abnormal response of the immunological system, especially of mucosal immunological system on antigens supplied per os. There are very complicated and still unexplained immunological mechanisms, which lead to hypersensitivity reaction. Most often food hypersensitivity is identified as the effect of atopy, which is connected with(More)
BACKGROUND The possibility of detection of lymphocytes T specific sensitivity after contact with the allergen (mainly food allergen) even in early age of children has been reported in this paper. METHODS/DATA BASE This is the literature review of basic applied methods such as: lymphocyte blastic transformation in allergen stimulated culture, macrophage(More)
The immonomodulatory mechanisms responsible for allergens tolerance in healthy subjects were described on the basis of the newest medical literature, including own papers and experience. It was detected that the same immunological mechanisms are built by specific immunotherapy. IL-10 and TGF-beta cooperate in the regulatory T-cell response to aeroallergens,(More)