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  • Santiago Fernandez Gonzalez, Mark O. Huising, +5 authors Geert F. Wiegertjes
  • Biology, Medicine
  • Developmental and comparative immunology
  • 2007
  • We studied a predictive model of gene expression induced by mechanical injury of fish skin, to resolve the confounding effects on the immune system induced by injury and skin parasite-specificExpand
  • Anna Nørholm Lundin, Ronald Dijkman, +12 authors Edward Trybala
  • Biology, Medicine
  • PLoS pathogens
  • 2014 (First Publication: 1 May 2014)
  • Coronaviruses raise serious concerns as emerging zoonotic viruses without specific antiviral drugs available. Here we screened a collection of 16671 diverse compounds for anti-human coronavirus 229EExpand
  • Maria Forlenza, Joern P. Scharsack, Neli M. Kachamakova, A. Taverne-Thiele, Jan H.W.M. Rombout, Geert F. Wiegertjes
  • Medicine, Biology
  • Molecular immunology
  • 2008 (First Publication: 1 June 2008)
  • Tyrosine nitration is a hallmark for nitrosative stress caused by the release of reactive oxygen and nitrogen species by activated macrophages and neutrophilic granulocytes at sites of inflammationExpand
  • Maria Forlenza, Stefan Magez, J. P. Scharsack, Andreas Westphal, H. F. J. Savelkoul, G. F. Wiegertjes
  • Biology, Medicine
  • The Journal of Immunology
  • 2009 (First Publication: 15 October 2009)
  • Functional characterization of TNF-α in species other than mammalian vertebrates is limited, and TNF-α has been studied in a limited number of fish species, primarily in vitro using recombinantExpand
  • Inge R. Fink, Erica L Benard, Trudi T. Hermsen, Annemarie H. Meijer, Maria Forlenza, Geert F. Wiegertjes
  • Medicine, Biology
  • Molecular immunology
  • 2015 (First Publication: 1 February 2015)
  • CD36 is a scavenger receptor which has been studied closely in mammals where it is expressed by many different cell types and plays a role in highly diverse processes, both homeostatic andExpand
  • Maria Carla Piazzon, Huub Savelkoul, Danilo Pietretti, Geert F. Wiegertjes, Maria Forlenza
  • Biology, Medicine
  • The Journal of Immunology
  • 2015 (First Publication: 1 January 2015)
  • In the current study, we investigated the effects of carp Il10 on phagocytes and lymphocytes. Carp Il10 shares several prototypical inhibitory activities on phagocytes with mammalian IL-10, includingExpand
    Abstract Mammalian naive CD8+ T cells are activated by antigen (signal 1) and CD28 costimulation (signal 2) to undergo several rounds of cell division, but programming for survival, effector functionExpand