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OBJECTIVE To examine whether psychological distress predicts IVF treatment outcome as well as whether IVF treatment outcome predicts subsequent psychological distress. DESIGN Prospective cohort study over an 18-month period. SETTING Five community and academic fertility practices. PATIENT(S) Two hundred two women who initiated their first IVF cycle.(More)
OBJECTIVE To assess depression, anxiety, and anger as well as the variance that these emotions share (conceptualized as negative affect) in relationship to high-frequency heart rate variability (HF-HRV), a specific indicator of parasympathetic cardiac autonomic function related to premature cardiovascular morbidity and mortality. Although individual trait(More)
OBJECTIVE To examine the influence of parent-child relationship quality on the association between illness-related functional status and depressive symptoms in children with asthma. METHODS Questionnaire data were collected from the child, caregiver, and physician. Fifty-five children with asthma (8-17 years of age), their caregivers, and physicians(More)
Exaggerated cardiovascular reactivity to behavioral challenges among otherwise healthy individuals has been associated with carotid atherosclerosis. We evaluated whether a similar relationship exists among hypertensives, who are at a heightened atherosclerotic risk. Untreated, hypertensive men (n=251; age range, 40 to 70 years; 197 white, 54 black)(More)
BACKGROUND We reported previously that the socio-economic status (SES) of individuals predicts variation in brain serotonergic responsivity, as assessed by neuropharmacological challenge in an adult community sample, and that this association is qualified by allelic variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR). Here we(More)
This study documents psychological problems in obese adolescents seeking bariatric surgery with laparoscopic adjustable gastric band. Depression, self-harm, suicidal ideation, anxiety, and bullying were reported frequently. Professionals will need to carefully assess adolescents for high-risk behaviors and provide appropriate follow-up care if these(More)
OBJECTIVE To examine the effect of length variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) on individual differences in cardiovascular response to psychological challenge. METHODS Heart rate (HR) and systolic and diastolic blood pressure (SBP, DBP) responses to computerized versions of two psychological challenges, the(More)
OBJECTIVE To determine whether greater childhood adversity relates to younger menarcheal age; whether younger menarcheal age relates to increased CVD risk; and whether greater childhood adversity relates to increased CVD risk, directly or indirectly (mediated by menarcheal age). METHODS Among 650 pre-menopausal women (ages 25-45; M=34.9[5.6]), SEM was(More)
OBJECTIVE To determine whether anger-related personality traits are associated with carotid artery atherosclerosis in untreated hypertensive patients. METHODS Study participants were 237 men with elevated blood pressure (systolic 140-180 mm Hg and/or diastolic 90-110 mm Hg) but untreated for hypertension. Average age was 56 years; 80% of subjects were(More)
OBJECTIVE The objective of the study was to characterize the backgrounds of women who have repeat abortions. STUDY DESIGN In a cross-sectional study of 259 women (mean age, 35.2 ± 5.6 years), the relation between adverse experiences in childhood and risk of having 2 or more abortions vs 0 or 1 abortion was examined. Self-reported adverse events occurring(More)