Learn More
The basic prerequisite for an efficient breeding program to improve levels of resistance to pathogens in plants is the identification of genes controlling the resistance character. If the response to pathogens is under the control of a multilocus system, the utilization of molecular markers becomes essential. Stalk and ear rot caused by Gibberella zeae is a(More)
Clones derived from Beta vulgaris and Beta maritima were assayed for their ability to detect restriction fragment length polymorphisms (RFLPs) in different beet accessions. The clones able to detect polymorphism were used as genetic markers to assess the degree of genetic variation existing between and within different species of the genus Beta. The data(More)
The Pretargeted Antibody-Guided RadioImmunoTherapy (PAGRIT) method is based on intravenous, sequential administration of a biotinylated antibody, avidin/streptavidin and (90)Y-labelled biotin. The hybridoma clone producing the monoclonal antitenascin antibody BC4, previously used for clinical applications, was found not suitable for further development(More)
PURPOSE In the pretargeted antibody-guided radioimmunotherapy (PAGRIT) system, the combined use of two different antibodies directed against the same tumor antigen could represent a valid approach for improving tumor targeting and therapeutic efficacy. We developed a novel monoclonal antitenascin antibody, ST2485, and studied its biochemical and functional(More)
S1 Assessing prognosis for early breast cancer: clinical versus genetic profiles GN Hortobagyi Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Breast Cancer Research 2007, 9(Suppl 1):S1 (doi: 10.1186/bcr1684) Since the introduction of systemic adjuvant chemotherapy (ACT) and endocrine therapy in the(More)
Adaptor-specific polymerase chain reaction (PCR) was used to amplify 3 different products, termed variant A, B, and C, from the seed-specific class (SnRK1b) of the sucrose nonfermenting-1-related protein kinase gene family (SnRK1) of different Hordeum species and cultivars of barley (Hordeum vulgare). Standard PCR or reverse transcription-PCR (RT-PCR) at a(More)
S1 Assessing prognosis for early breast cancer: clinical versus genetic profiles GN Hortobagyi Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Breast Cancer Research 2007, 9(Suppl 1):S1 (doi: 10.1186/bcr1684) Since the introduction of systemic adjuvant chemotherapy (ACT) and endocrine therapy in the(More)
  • 1