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Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study.
This proof-of-concept study provides clues that hepatic USPio uptake in patients with NASH is decreased and that USPIO MR imaging can be used to differentiate NASH from simple steatosis.
Novel CREB3L3 Nonsense Mutation in a Family With Dominant Hypertriglyceridemia
This investigation investigated a family in which hypertriglyceridemia displayed an autosomal dominant pattern of inheritance and identified a novel pathogenic mutation in CREB3L3 gene in a family with dominant hypertrigenia with a variable pattern of penetrance.
Lomitapide: a novel drug for homozygous familial hypercholesterolemia
Lomitapide was generally well tolerated and the most common adverse events in the Phase III trial were gastrointestinal and hepatic events.
Lomitapide Reduced secretion of ApoB-containing lipoproteins from the liver by MTP inhibition reduces the amount of LDL-C and TG in the blood by 50% and 45% respectively.
A Lesson from a Fatal Case of Leptospirosis Author ’ s Details :
This work results in new insights into the rationale behind the continued use of EMT in the diagnosis and treatment of central nervous system disorders.