Maria D . Panno

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PURPOSE To (a) study the optimal timing and dosing for ultrasmall superparamagnetic iron oxide particle (USPIO)-enhanced magnetic resonance (MR) imaging of the liver in nonalcoholic fatty liver disease, (b) evaluate whether hepatic USPIO uptake is decreased in nonalcoholic steatohepatitis (NASH), and (c) study the diagnostic accuracy of USPIO-enhanced MR(More)
OBJECTIVE Cyclic AMP responsive element-binding protein 3-like 3 (CREB3L3) is a novel candidate gene for dominant hypertriglyceridemia. To date, only 4 kindred with dominant hypertriglyceridemia have been found to be carriers of 2 nonsense mutations in CREB3L3 gene (245fs and W46X). We investigated a family in which hypertriglyceridemia displayed an(More)
Unità Operativa di Medicina Interna e Dislipidemie Genetiche, AOUP “Paolo Giaccone”, Palermo Italy c Unità Operativa di Diagnostica Specialistica Malattie Diffusive, AOUP “Paolo Giaccone”, Palermo Italy *These two authors contributed equally to this work # Corresponding author: Maurizio Averna, M.D. Professor of Internal Medicine Dipartimento Biomedico di(More)
High plasma triglyceride concentration is a biomarker of a variety of familial and sporadic metabolic disorders. According to a recent proposed simplified definition of the hypertriglyceridemic states, fasting triglyceride plasma levels <2 mmol/L (175 mg/dL) can be considered normal while triglyceride levels between 2 to 10 mmol/L (175–885 mg/dL) and >10(More)
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