Maria-Christina Kyrtsonis

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UNLABELLED Neovascularisation and bone resorption are related to myeloma disease activity. OBJECTIVES To investigate the possible prognostic importance of serum syndecan-1, basic fibroblast growth factor (bFGF) and osteoprotegerin (OPG) levels, the relationship between them, with parameters of disease activity and the effect of treatment on their levels.(More)
Childhood idiopathic thrombocytopenic purpura (ITP) resolves usually after the first episode, although it may recur, and in 10% to 20% of patients develops into a chronic disorder. Evidence of the immunoregulatory role of Th1/Th2 responses in autoimmune diseases prompted us to perform a prospective study of Th1/Th2 gene expression profiles and transforming(More)
Primary cutaneous marginal zone lymphoma (PCMZL) is an indolent disease. Treatment options include excision, local irradiation, interferon-alpha or chemotherapy. We present two patients with PCMZL and multiple skin lesions successfully treated with intralesional administration of the anti-CD20 monoclonal antibody rituximab. The first presented with four red(More)
In the present study, we assessed the clinical and pathological data of 76 patients with the diagnosis of non-gastric extranodal marginal zone B-cell lymphoma. The most commonly affected sites were salivary glands, skin, ocular adnexa, lung, intestine and Waldeyer's ring. Ann Arbor stage I disease was present in 39 patients (51%), stage II in 10 (13%) and(More)
Waldenstrom's macroglobulinemia (WM) is characterized by lymphoplasmacytic infiltration of bone marrow and/or other tissues and by the presence of serum monoclonal immunoglobulin M ([IgM], without cutoff limit). Differential diagnosis from other B-cell disorders (BCDs) is usually easy based on clinical, morphologic, histopathologic, immunophenotypic, and(More)
Lymphomas associated with Warthin's tumor (WT) are extremely uncommon and the majorities are of B cell type. We report the simultaneous occurrence of T-cell lymphoblastic lymphoma (T-LBL) and WT in an 81-year-old patient, who presented with fever, night sweats and enlargement of the right parotid gland. The parotidectomy specimen showed a WT with extensive(More)
couple of hours later, there was swelling and reddening of the margins of the ulcers, frequently accompanied by fever up to 38°C. These symptoms lasted for a few hours and subsided spontaneously or with the help of minor analgesics. The patients tolerated this inconvenience, because they soon saw a favorable response. In fact, the latter was dramatic in(More)
Indolent B-cell non-Hodgkin’s lymphomas (IBCNHL) represent a heterogenous group of chronic diseases [1]. Follicular lymphomas grades 1 and 2 (FL1/2) are by far the most common, accounting for approximately 20% of all NHL worldwide. Indolent IBC-NHL also include small lymphocytic lymphoma (SLL), which is the tissue counterpart of B-chronic lymphocytic(More)
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