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Journals and Conferences
Particle bombardment is a physical method for cell transformation in which high density, sub-cellular sized particles are accelerated to high velocity to carry DNA/RNA into living cells. It is a… (More)
Studies of structure-activity relationships for the linker in a new series of metabotropic glutamate receptor 5 antagonists are presented together with in vitro and in vivo pharmacokinetic data.
According to the cancer stem cell (CSC)/cancer-initiating cell hypothesis, glioma development is driven by a subpopulation of cells with unique tumor-regenerating capacity. We have characterized… (More)
In human and ovine fetuses, glucocorticoids stimulate leptin secretion, although the extent to which leptin mediates the maturational effects of glucocorticoids on pulmonary development is unclear.… (More)
The racemic triflate derivatives 5-8 of the 5-, 6-, 7-, and 8-hydroxylated 2-(di-n-propylamino)-teralins 1-4 were shown to possess similar pharmacological profiles to their phenolic counterparts in… (More)
Elina Helenius*, Maria Boije*, Viola Niklander-Teeri*, E. Tapio Palva 3 and Teemu Teeri, 1 Department of Biosciences, Division of Genetics, P. O. Box 56, FIN-00014 University of Helsinki 2 Department… (More)
Synthesis and some structure-activity relationships for a new series of propargyl ethers as mGluR5 antagonists are reported.
The effects of endogenous and synthetic glucocorticoids on fetal lung maturation are well-established, although the role of leptin in lung development before birth is unclear. This study examined… (More)