Maria Beatriz da Fonte Kohek

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OBJECTIVE To investigate the presence of FSH receptor gene mutations in women with premature ovarian failure (POF). DESIGN Clinical and molecular studies. SETTING Research laboratory in a university setting. PATIENT(S) Fifteen 46,XX women with POF and 42 normal fertile controls. INTERVENTION(S) Exon 7 was amplified and digested with BsmI to screen(More)
Despite recent advances in molecular genetics, the pituitary adenoma initiation, development, progress, and the molecular basis of their unique features are still poorly understood. In this sense, it is proposed that stem cell could be involved in pituitary adenoma tumorigenesis. It is suggested that TP63 has important functions in stem cells, and it may(More)
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