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- Mark A. Horsfield, Stefania Sala, +6 authors Massimo Filippi
- NeuroImage
- 2010
A new semi-automatic method for segmenting the spinal cord from MR images is presented. The method is based on an active surface (AS) model of the cord surface, with intrinsic smoothness constraints.… (More)
- Maria Assunta Rocca, Antonia Ceccarelli, +6 authors Massimo Filippi
- Stroke
- 2006
BACKGROUND AND PURPOSE
In migraine patients, functional imaging studies have shown changes in several brain gray matter (GM) regions. However, 1.5-T MRI has failed to detect any structural… (More)
- Giancarlo Comi, Douglas R. Jeffery, +4 authors Massimo Filippi
- The New England journal of medicine
- 2012
BACKGROUND
Two proof-of-concept clinical trials have provided evidence that laquinimod reduces disease activity in patients with relapsing-remitting multiple sclerosis.
METHODS
We conducted a… (More)
- Maria Assunta Rocca, Paola Valsasina, +4 authors Massimo Filippi
- Neurology
- 2012
OBJECTIVES
Given that multiple sclerosis (MS) hits diffusely the brain hemispheres, we hypothesized that this should result in a distributed pattern of functional connectivity (FC) abnormalities. To… (More)
- Antonia Ceccarelli, Maria Assunta Rocca, +4 authors Massimo Filippi
- NeuroImage
- 2008
To assess regional grey matter (GM) changes in a large cohort of multiple sclerosis (MS) patients with different clinical phenotypes, using voxel-based morphometry (VBM) and their correlation with… (More)
- Massimo Filippi, Paola Valsasina, Paolo Misci, Andrea Falini, Giancarlo Comi, Maria Assunta Rocca
- Human brain mapping
- 2013
OBJECTIVES
To investigate, using resting state (RS) functional MRI (fMRI), gender-related differences of functional connectivity (FC) and functional network connectivity (FNC) of the human brain.
… (More)
- Elisabetta Pagani, Maria Assunta Rocca, +4 authors Massimo Filippi
- AJNR. American journal of neuroradiology
- 2005
BACKGROUND AND PURPOSE
Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes.
METHODS
Dual-echo… (More)
- Maria Assunta Rocca, Bruno Colombo, +5 authors Massimo Filippi
- The Lancet. Neurology
- 2005
BACKGROUND
Movement-associated cortical reorganisation is known to occur in multiple sclerosis (MS). We aimed to define the development of such cortical reorganisation by comparing data from patients… (More)
- Massimo Filippi, Gianna Carla Riccitelli, +8 authors Maria Assunta Rocca
- Radiology
- 2012
PURPOSE
To evaluate brain changes after cognitive rehabilitation in patients with clinically stable relapsing-remitting (RR) multiple sclerosis (MS) by using neuropsychologic assessment and… (More)
- Rohit Bakshi, Alan J. Thompson, +7 authors Massimo Filippi
- The Lancet. Neurology
- 2008
Many promising MRI approaches for research or clinical management of multiple sclerosis (MS) have recently emerged, or are under development or refinement. Advanced MRI methods need to be assessed to… (More)