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- Federica Agosta, Elisabetta Pagani, +5 authors Massimo Filippi
- Human brain mapping
- 2007
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive and simultaneous degeneration of upper and lower motor neurons. The pathological process associated… (More)
- Maria Assunta Rocca, Antonia Ceccarelli, +6 authors Massimo Filippi
- Stroke
- 2006
BACKGROUND AND PURPOSE
In migraine patients, functional imaging studies have shown changes in several brain gray matter (GM) regions. However, 1.5-T MRI has failed to detect any structural… (More)
- Mark A. Horsfield, Stefania Sala, +6 authors Massimo Filippi
- NeuroImage
- 2010
A new semi-automatic method for segmenting the spinal cord from MR images is presented. The method is based on an active surface (AS) model of the cord surface, with intrinsic smoothness constraints.… (More)
- Giancarlo Comi, D. Ross Jeffery, +4 authors Massimo Filippi
- The New England journal of medicine
- 2012
BACKGROUND
Two proof-of-concept clinical trials have provided evidence that laquinimod reduces disease activity in patients with relapsing-remitting multiple sclerosis.
METHODS
We conducted a… (More)
- Maria Assunta Rocca, Paola Valsasina, +4 authors Massimo Filippi
- Neurology
- 2012
OBJECTIVES
Given that multiple sclerosis (MS) hits diffusely the brain hemispheres, we hypothesized that this should result in a distributed pattern of functional connectivity (FC) abnormalities. To… (More)
- Massimo Filippi, Paola Valsasina, Paolo Misci, Andrea Falini, Giancarlo Comi, Maria Assunta Rocca
- Human brain mapping
- 2013
OBJECTIVES
To investigate, using resting state (RS) functional MRI (fMRI), gender-related differences of functional connectivity (FC) and functional network connectivity (FNC) of the human brain.
… (More)
- Antonia Ceccarelli, Maria Assunta Rocca, +4 authors Massimo Filippi
- NeuroImage
- 2008
To assess regional grey matter (GM) changes in a large cohort of multiple sclerosis (MS) patients with different clinical phenotypes, using voxel-based morphometry (VBM) and their correlation with… (More)
- Massimo Filippi, Maria Assunta Rocca, +4 authors Giancarlo Comi
- NeuroImage
- 2002
Although fatigue is a common and troublesome symptom of multiple sclerosis (MS), its pathogenesis is poorly understood. In this study, we used functional magnetic resonance imaging (fMRI) to test… (More)
- Rohit Bakshi, Alan J. Thompson, +7 authors Massimo Filippi
- The Lancet. Neurology
- 2008
Many promising MRI approaches for research or clinical management of multiple sclerosis (MS) have recently emerged, or are under development or refinement. Advanced MRI methods need to be assessed to… (More)
- Massimo Filippi, Gianna Carla Riccitelli, +8 authors Maria Assunta Rocca
- Radiology
- 2012
PURPOSE
To evaluate brain changes after cognitive rehabilitation in patients with clinically stable relapsing-remitting (RR) multiple sclerosis (MS) by using neuropsychologic assessment and… (More)