Maria Aparecida da Glória

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Methylenetetrahydrofolate reductase (MTHFR: EC 1.5.1.20) polymorphisms are associated to acute lymphoid leukemia in different populations. We used the polymerase chain reaction and the restriction fragment length polymorphism method (PCR-RFLP) to investigate MTHFR C677T and A1298C polymorphism frequencies in 67 patients with chronic myeloid leukemia (CML),(More)
BACKGROUND The immunosuppressor cyclosporine A (CsA) presents the nephrotoxicity as its major side effect that is mostly attributed to a renal vasoconstriction. This may be due to an excessive generation of vasoconstrictors like reactive oxygen species (ROS), or due to a reduction of vasodilators such as the nitric oxide, which in turn, can be caused by(More)
The research problem was: what are the effects of preparation for mastectomy/hysterectomy on women's self-care behaviors during the immediate post-operative period, and 1 month after surgery? Study subjects were 60 women, 30 mastectomy and 30 hysterectomy, equally divided into an experimental and control group. The independent variable, structured teaching,(More)
PURPOSE To evaluate the importance of the presence of 3T3 fibroblasts for establishing limbal epithelial cultures from cell suspension obtained from corneo-scleral rims (CSR). METHODS Corneo-scleral rims from different donors (n=6) had their posterior stroma and endothelium stripped away. Each corneo-scleral rim was divided into three equal segments that(More)
Hypoxia activates endothelial cells by the action of reactive oxygen species generated in part by cyclooxygenases (COX) production enhancing leukocyte transmigration. We investigated the effect of specific COX inhibition on the function of endothelial cells exposed to hypoxia. Mouse immortalized endothelial cells were subjected to 30 min of oxygen(More)
Gustavo Augusto Seabra Barbosa1 Paulo Cézar Simamoto Junior2 Alfredo Júlio Fernandes Neto3 Maria da Glória Chiarello de Mattos4 Flávio Domingues das Neves5 1DDS, MS, PhD Student, School of Dentistry of Ribeirão Preto, University of Sao Paulo. Substitute Professor at Department of Fixed Prosthodontics, Occlusion and Dental Materials, Federal University of(More)
Background:Diseases of adulthood, such as diabetes and hypertension, may be related to changes during pregnancy, particularly in kidney. We hypothesized that acute kidney injury progresses more rapidly in cases of fetal programming.Methods:Diabetic dams’ offspring were divided into: CC (controls, receiving vehicle); DC (diabetics, receiving vehicle); CA(More)
Aberrant promoter hypermethylation is common in head and neck cancer and may be useful as a marker for cancer cells. We examined whether cells with tumor-specific aberrant DNA-methylation might be found in the saliva of affected patients. We tested 30 patients with primary head and neck tumors using methylation-specific PCR searching for promoter(More)
The research aimed to clarify the relationships between spirituality, gender, and drug use among undergraduate students of one university in Barbados. A quota sample of 250 students was required from the Faculty of Social Sciences as the study was part of a larger multi-centric study involving students from the Faculty of Social Sciences from seven other(More)
Obesity and its consequences can damage the kidney over time. However, less is known about the impact of developing overweight/obesity during childhood on the kidney in adulthood and the renal impact of a superimposed acute kidney injury (AKI). This study evaluated the effect of obesity induced by a high-fat diet initiated soon after weaning on the adult(More)