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OBJECTIVE To compare a combination of epidural fentanyl and bupivacaine with bupivacaine alone for epidural analgesia in labour and to evaluate factors in addition to analgesia that may influence maternal satisfaction. DESIGN A prospective randomised pilot study. SETTING Birmingham Maternity Hospital. SUBJECTS 85 primiparous women who requested(More)
OBJECTIVE To determine the pharmacokinetics and pharmacodynamics of the neuromuscular blocking agent atracurium besylate in patients with fulminant hepatic failure (FHF). DESIGN Open study of patients receiving atracurium infusions to facilitate mechanical ventilation. SETTING Intensive care unit in a tertiary referral university teaching hospital. (More)
Forty healthy parturients scheduled for elective Caesarean section were randomly allocated to receive either 0.3 ml 0.9% saline (control group, n = 20), or 15 micrograms (0.3 ml) fentanyl (treatment group, n = 20) added to 2.5 ml 0.5% hyperbaric bupivacaine given intrathecally in the sitting position. A sensory block to T4 was achieved after 6.5 min in(More)
  • Quad Collaboration, M L Brown, +7 authors E Y S Wu
  • 2009
We present an improved analysis of the final dataset from the QUaD experiment. Using an improved technique to remove ground contamination, we double the effective sky area and hence increase the precision of our CMB power spectrum measurements by ∼ 30% versus that previously reported. In addition, we have improved our modeling of the instrument beams and(More)
Typical grammar checking software use some form of natural language parsing to determine if errors exist in the text. If a sentence is found ungrammatical, the grammar checker usually seeks a single grammatical error as an explanation. For non-native speakers of English, it is possible that a given sentence contain multiple errors and grammar checkers may(More)
We report results from the second and third seasons of observation with the QUaD experiment. Angular power spectra of the Cosmic Microwave Background are derived for both temperature and polarization at both 100 GHz and 150 GHz, and as cross frequency spectra. All spectra are subjected to an extensive set of jackknife tests to probe for possible systematic(More)
We examined the pharmacokinetics and pharmacodynamics of atracurium besylate and its metabolites in children after orthotopic liver transplantation (OLT), as a suitable model for critically ill children. Ten children were studied after OLT on return to the intensive care unit (ICU). The mean (range) age was 36 (7-78) months, and weight 6-24.2 kg. Atracurium(More)
Either 100 micrograms fentanyl or 2 ml saline was added to 0.5% bupivacaine administered epidurally for elective Caesarean section in 30 patients, in a double-blind randomised study. Bupivacaine 0.5% was administered until a complete sensory block was established extending to the 4th thoracic dermatome. One of the patients who received epidural fentanyl(More)