Margarida Morais Marques

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Background and study aims Clinical impact of single-balloon enteroscopy (SBE) is fairly known, as well as its diagnostic yield comparing with other small bowel gastrointestinal investigations. This study represents a contribution to better understand it and is designed to evaluate SBE efficacy and degree of concordance with previous evaluation of small(More)
BACKGROUND Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe(More)
INTRODUCTION Obesity-related comorbidities are present in young obese children, providing a platform for early adult cardiovascular disorders. OBJECTIVES To compare and correlate markers of adiposity to metabolic disturbances, vascular and cardiac morphology in a European pediatric obese cohort. METHODS We carried out an observational and transversal(More)
BACKGROUND AND STUDY AIMS One of the indications for capsule endoscopy (CE) is the detection of proximal small bowel (SB) involvement in Crohn's disease (CD) patients. Our aim was to assess clinical, laboratory and endoscopic predictors associated with proximal SB involvement in CD patients submitted to CE. PATIENTS AND METHODS Retrospective multicenter(More)
Both cancer and tumour-associated host cells are exposed to ionizing radiation when a tumour is subjected to radiotherapy. Macrophages frequently constitute the most abundant tumour-associated immune population, playing a role in tumour progression and response to therapy. The present work aimed to evaluate the importance of macrophage-cancer cell(More)
Radiotherapy is a major therapeutic weapon in lung cancer. However, the resistance to radiotherapy is frequent. The microRNAs of the miR-34 family, miR-34a, miR-34b and miR-34c, described as effector molecules in the cellular response to activation of P53, have low expression levels in lung cancer [1]. The mRNA of the anti-apoptotic protein BCL-2 is among(More)
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