Margaret S. Wu

Mari Rios Candelore1
Bei B. Zhang1
Sajjad A. Qureshi1
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  • James Mu, Sajjad A. Qureshi, Edward J. Brady, Eric S. Muise, Mari Rios Candelore, Guoqiang Jiang +9 others
  • 2012
Hyperglucagonemia is implicated in the pathophysiology of hyperglycemia. Antagonism of the glucagon receptor (GCGR) thus represents a potential approach to diabetes treatment. Herein we report the characterization of GRA1, a novel small-molecule GCGR antagonist that blocks glucagon binding to the human GCGR (hGCGR) and antagonizes glucagon-induced(More)
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