Margaret M Pearson

Learn More
Na(+)-independent K(+)-Cl(-) cotransporters function in the regulation of cell volume, control of CNS excitability and epithelial ion transport. Several K(+)-Cl(-) cotransporter isoforms are expressed in the nervous system, and KCC3 in particular is expressed at significant levels in both the brain and spinal cord. The cellular localization of this(More)
Protein phosphatase 2A (PP2A) is a heterotrimeric protein serine/threonine phosphatase and is involved in a broad range of cellular processes. PPP2R5D is a regulatory B subunit of PP2A and plays an important role in regulating key neuronal and developmental regulation processes such as PI3K/AKT and glycogen synthase kinase 3 beta (GSK3β)-mediated cell(More)
Amphotericin B (AMB) is an antifungal agent that possesses immunomodulatory properties that may contribute to its infusion-related toxicity and activity. It has previously been shown to induce the expression of genes encoding the cytokines interleukin (IL)-1 beta and tumour necrosis factor (TNF)-alpha and the chemokines IL-8 and macrophage inflammatory(More)
a peer-reviewed journal devoted to bridging the gap between academic research and policymaking on issues related to the Asia-Pacific
It is widely believed within China and beyond that the political and economic future of the country will be shaped in important ways by the expansion of new, powerful information and communications technologies (ICTs). However, there is not agreement on what the precise impacts will be, nor how one should analyze and understand the m. This essay makes two(More)
  • 1