Margaret H. Pui

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PURPOSE To assess imaging features of granulocytic sarcoma (GS) in children with myelogenous leukemia. MATERIALS AND METHODS Retrospectively analyzed were radiographs, bone scintigrams, ultrasound (US) scans, computed tomography (CT) scans, and magnetic resonance (MR) images obtained in 30 patients with acute and one with chronic myelogenous leukemia. (More)
BACKGROUND AND PURPOSE Pyogenic and tuberculous spondylitis can mimic malignancy. The purpose of this study was to deter mine the efficacy of diffusion-weighted magnetic resonance imaging in differentiating spinal infection and malignancy. METHODS Fifty-one consecutive patients with suspected spinal infection or malignancy were enrolled in the study.(More)
OBJECTIVE The characteristics of intracranial tuberculoma on computed tomography (CT) and magnetic resonance imaging (MRI) are not well known. The authors reviewed the features of tuberculoma on CT scans and MRI. The authors also correlated the MRI characteristics on various pulse sequences with neuropathological findings. METHODS The charts of patients(More)
Magnetization transfer (MT) imaging has been used to characterize tissues. A prospective analysis of magnetization transfer ratio (MTR) was performed on 107 patients with brain tumors, infection, and infarction to determine its efficacy in differential diagnosis. MTRs of brain tumor, infection, and infarction were significantly lower than those of normal(More)
 Objective To prospectively compare inversion recovery (IR) fast spin-echo (FSE) with T1-weighted spin-echo (SE) and T2-weighted chemical-shift fat-saturated (FS) FSE magnetic resonance sequences in the detection of bone marrow abnormality. Design. Twenty-nine sets of T1-weighted SE [400–640/10–20 (TR/TE)], T2-weighted FS-FSE [2400–3800/91–112/8(More)
OBJECTIVE To estimate the prevalence of bone and soft tissue abnormalities in asymptomatic knees using peripheral magnetic resonance imaging (pMRI) and to examine the relationship between these abnormalities and Kellgren-Lawrence (K-L) graded X-rays. METHOD Volunteers (20-68 years) with no history of knee pain, injury or bone or joint disease were(More)
To investigate the efficacy of diffusion-weighted MRI (DWI) in differentiating recurrent tumor from chronic inflammation and fibrosis after cystectomy or transurethral resection of bladder cancer. Eleven patients with suspected tumor recurrence underwent pelvic DWI and dynamic contrast-enhanced (DCE) MRI at 3 months to 7 years following bladder cancer(More)
The purpose of this study was to determine the efficacy of diffusion-weighted imaging (DWI) and magnetization transfer imaging (MTI) in the differential diagnosis of brain infarct, infection, hamartoma, and tumor in 106 children. The apparent diffusion coefficients (ADCs) and magnetization transfer ratios (MTRs) of the lesions were compared using(More)
PURPOSE To assess the feasibility of diffusion tensor imaging (DTI) of normal kidneys and the influence of hydration state. MATERIALS AND METHODS Ten healthy volunteers underwent renal DTI after fasting for 12 hours and 4 hours, without fasting, and following water diuresis. Medullary and cortical apparent diffusion coefficient (ADC) and fractional(More)
BACKGROUND Patients with cystic fibrosis (CF) are at risk for early bone loss, and demonstrate increased risks for vertebral fractures and kyphosis. A multicenter, randomized, controlled trial was conducted to assess the efficacy, tolerability, and safety of therapy with oral alendronate (FOSAMAX; Merck; Whitehouse Station, NJ) in adults with CF and low(More)