Margaret G Dukes

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A World Health Organisation (European Regional Office) working party has been established to review the progress of clinical pharmacology in European countries. As part of this review a questionnaire on the teaching of clinical pharmacology was sent to the Deans of all 350 medical schools in the region. Very few replies were received from U.S.S.R., Greece(More)
Two experiments were conducted using 21-day-old, commercial-strain broilers to determine the effect of various commercial pigmentation products on pigmentation and bird performance. Birds received finisher/withdrawal diets that included 8% corn gluten meal or either a 2.5 or 5.0% substitution of gluten meal with Liquid OroGlo5, Dry Oroglo10, or(More)
PURPOSE To assess accuracy of mothers' understanding of their newborns' genetic risk for type 1 diabetes and to identify predictors of the comprehension and retention of genetic information. METHODS Mothers of 435 newborns genetically screened at birth were informed of the infant's risk for type 1 diabetes using a standard script that provided both(More)
In this study the use of prescribed drugs before, during and after pregnancy is described. The study is based on data obtained from pharmacy records of 1,948 women who delivered a live-born infant. Different measures to evaluate drug exposure are used. During the nine months of pregnancy 86% of the women used on average 4.2 prescriptions. During the course(More)
The initiative taken by the Government of the Netherlands in 2003 to develop a basis for a worldwide public health approach to the development of new medicines is welcome. Although new medicines have continued to enter the market during the half century in which public policies in this field have come to maturity, it is no secret that the development(More)
The number of marketed non-steroidal anti-inflammatory agents varies widely from one European country to another, partly as a consequence of differing regulatory policies. During a four-year period, nine of 18 applications to market such drugs in the Netherlands failed; the remaining nine compounds were all licenced; in all, 22 single drug entities of this(More)
We have compared the reliability of the information about drug therapy and pregnancy retrieved by interviewing patients with that distilled from pharmacy records. In the initial phase of each interview we used the internationally accepted open-ended technique, and extended this with an indication-oriented set of questions and then a set of specific(More)