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The development of atherosclerotic lesions was studied in pigs aged 4 to 54 months with inherited hyperlow-density lipoprotein (LDL) and hypercholesterolemia (IHLC pigs). These pigs bear the Lpb5 and(More)
BACKGROUND Aliskiren is the first in a new class of orally effective renin inhibitors for the treatment of hypertension. METHODS In 569 patients with mild-to-moderate hypertension, blood pressure(More)
We reported earlier that a complex familial hypercholesterolemia (c-FHC) phenotype characterized by elevated levels of total plasma cholesterol (TC) and apoB and reduced levels of HDL cholesterol(More)