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Objective determination of spermatogenesis has been accomplished by quantitative testicular biopsy, which, although laborious, has served as the standard for spermatogenic assessment. Aspiration deoxyribonucleic acid (DNA) flow cytometry of the testis, however, has simplified this determination, and has correlated with indirect hormonal parameters of(More)
This study identifies factors that are associated with the risk of access thrombosis in 267 new hemodialysis patients. There are few longitudinal studies evaluating the risk of access thrombosis despite the need for long-term use of the access for maintenance hemodialysis. We used a prospective design following patients from 26 providers in Renal Network(More)
The purpose of this study was to evaluate inadequate hemodialysis risk in patients with body weights in the upper quartile of a sample distribution using the urea reduction ratio (URR). Using a case-control design and a simple random sample (n = 315) of hemodialysis (HD) patients, postdialysis weights were divided into quartiles based with a cut-off value(More)
Development and initial validation of the FACES of fatigue and sleepiness adjective checklist. An initial item pool of 65 adjectives, descriptive of fatigue, sleepiness and related deprivation states, was developed and administered to 372 individuals referred by their family physicians for psychiatric investigation and treatment of severe insomnia.(More)
End Stage Renal Disease Network 12 regularly collects information describing the Medicare dialysis population within its boundaries (Iowa, Nebraska, Missouri, and Kansas). Hoping to foster a regional quality improvement program, Network 12 began calculating provider specific mortality rates in 1988. These rates were extremely variable, but small dialysis(More)
OBJECTIVE The purpose of this study was to compare clinical profiles and mortality risk of patients starting renal replacement therapy (RRT) across three Quetelet body mass index (BMI) classifications: lean, normal, and obese. SAMPLE/SETTING All patients applying for dialysis services using Health Care Financing Administration (HCFA) from 2728-U4 were(More)
Proportional hazards analyses assume that the magnitude of mortality risk for a predictor variable remains proportional over time. In a time-dependent model, the explanatory variable violates this assumption, and repeat observations are required to accommodate the change in risk that occurs over time. Using a retrospective cohort design, we tested the(More)
Spermatogenic abnormalities have been reported in the majority of men following spinal cord injury, and they contribute to the multifactorial etiology of reproductive dysfunction. Thus far, few have studied the seminiferous epithelium in this group of patients by objective criteria. While quantitative micrometry and flow cytometric analysis are accurate and(More)
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