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Acute extrapyramidal syndromes (EPS), including dystonia, parkinsonism, and akathisia, are associated with the use of virtually all neuroleptic agents. They may be alleviated by reducing the… (More)
2069 Background: S-CKD602 is a pegylated STEALTH liposomal formulation of CKD-602, a semi-synthetic analogue of camptothecin. Camptothecins are topoisomerase I interactive agents occurring in… (More)
1394 Introduction: STEALTH® liposomal (SL) formulations contain lipid conjugated to polyethylene glycol. SL formulations of anticancer agents have been designed to prolong the drug circulation time,… (More)
STUDY OBJECTIVE To determine the extent of platinum-DNA (Pt-DNA) adduct formation in peripheral white blood cells of children with cancer. DESIGN Prospective study. SETTING Pediatric research… (More)