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IntroductioIl An intriguing feature of the adult brain is its capacity for structural and functional modification in response to external stimuli. This plasticity of the adult nervous system has been the focus of research efforts for decades. The historical antecedents of ideas about brain changes in relation to experiential factors can been traced back to(More)
This paper is one of a series presenting right-left differences in the morphology of the rat forebrain, but this presentation differs from the previous ones by offering age-related changes in both sexes. Long-Evans rats were housed with the dam prior to weaning at 21 days of age and three to a cage thereafter. The ages of the animals studied were 6 to 7,(More)
Ten pairs of male Long-Evans rats living in nonenriched environments (3 rats per small cage) were transferred to either enriched environments (10 rats per large cage plus "toys") or nonenriched environments (2 rats per small cage) at 766 days of age. One hundred and thirty-eight days later, at 904 days of age, the cerebral cortical thickness from these(More)
This experiment studied cerebral cortical morphology in rats living in a crowded-enriched condition. Three groups of 60-day-old, male Long-Evans rats were divided accordingly: 12 rats, 3 per small cage (32 X 20 X 20 cm), standard colony condition; 12 rats in a single, large, enrichment cage with "toys" (70 X 70 X 45 cm), enriched condition; and 36 rats in a(More)
Neuron:glial ratios were determined in specific regions of Albert Einstein's cerebral cortex to compare with samples from 11 human male cortices. Cell counts were made on either 6- or 20-micron sections from areas 9 and 39 from each hemisphere. All sections were stained with the Klüver-Barrera stain to differentiate neurons from glia, both astrocytes and(More)