Margaret Biber

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Periventricular heterotopia (PH) is a human neuronal migration disorder in which many neurons destined for the cerebral cortex fail to migrate. Previous analysis showed heterozygous mutations in the X-linked gene filamin 1 (FLN1), but examined only the first six (of 48) coding exons of the gene and hence did not assess the incidence and functional(More)
Since 1986, 2,279 pregnant women were screened for anti Parvovirus B19 IgG and IgM antibodies. Of them 41% were seronegative, 54% had specific IgG but no IgM antibodies, indicating an infection in earlier life. Acute infection could be demonstrated by IgM antibody detection in 114 pregnant women (32% in the first, 54% in the second and 14% in the third(More)
Measles, mumps and rubella are common childhood diseases. Therefore, frequent and intense contact with children of preschool age may be associated with a higher infection risk for childcare providers. This overview summarizes current knowledge on possible adverse effects of these infections on pregnant women, pregnancy outcome and the fetus. Acute rubella(More)
We determined IgG antibodies against Human Herpesvirus-6 (strain Uganda 1102, M. D. Griffin, London) in the indirect immunofluorescence test in sera from 1105 persons of various age groups. Of these sera 570 were retested using HHV-6 strain St. W. (Prof. Schneweis, Bonn). We could confirm that maternal antibodies decrease between birth and six months of age(More)
Three patients had amnesia and confusion as presenting features of thalamic hemorrhage. They had a relatively benign clinical appearance and lacked characteristics of the syndrome usually associated with thalamic hemorrhage. We reviewed hypotheses regarding a mechanism for the amnesic syndrome and concluded that lesions involving the medial thalamic nucleus(More)
Endoscopy of the esophagus, stomach, and duodenum and stool examinations for ova and parasites were performed in 63 adult Peruvian patients with "hunger pain" (HP) and other dyspeptic symptoms. No lesion capable of provoking HP was found at endoscopy in 50 (78%) of the 63 patients. Only 7 (12%) of the patients had evidence of active or healed peptic ulcers.(More)