Margaret A. Pisani

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IMPORTANCE Little is known about functional trajectories of older persons in the year before and after admission to the intensive care unit (ICU) or how pre-ICU functional trajectories affect post-ICU functional trajectories and death. OBJECTIVES To characterize functional trajectories in the year before and after ICU admission and to evaluate the(More)
PURPOSE Although bronchoscopy has conventionally been performed using conscious sedation, advanced diagnostic techniques like endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), peripheral EBUS, and electromagnetic navigational bronchoscopy add to procedural complexity. The adaptation of these techniques by bronchoscopists of(More)
INTRODUCTION Delirium is a serious and prevalent problem in intensive care units (ICU). The purpose of this study was to develop a research algorithm to enhance detection of delirium in critically ill ICU patients using chart review to complement a validated clinical delirium instrument. METHODS Prospective cohort study of 178 patients 60 years and older(More)
  • M Pisani, Cristina Badarau, Giancarlo Corsetti, Filippo Ferroni, Andrea Gerali, Ricardo Mourinho Félix +2 others
  • 2010
We estimate a dynamic general equilibrium model of an open economy to measure the effects of alternative expansionary fiscal shocks on the trade balance in the euro area. We do find that expansionary fiscal shocks-both those on the expenditure and revenue side-induce a joint deterioration of the public sector balance and trade balance. The output(More)
BACKGROUND Accurate measurement of quality of life in older ICU survivors is difficult but critical for understanding the long-term impact of our treatments. Activities of daily living (ADLs) are important components of functional status and more easily measured than quality of life (QOL). We sought to determine the cross-sectional associations between(More)
In this article, the authors demonstrate a time-series analysis based on a hierarchical Bayesian model of a Poisson outcome with an excessive number of zeroes. The motivating example for this analysis comes from the intensive care unit (ICU) of an urban university teaching hospital (New Haven, Connecticut, 2002-2004). Studies of medication use among older(More)
BACKGROUND Each year in the United States an estimated 1.5 million people develop pleural effusions and approximately 178,000 thoracenteses (12%) are performed. While it has been established that malignant effusions are associated with increased mortality, the association between mortality and all-cause pleural effusions in a medical population has not been(More)
Of the 1.5 million people diagnosed with pleural effusion in the USA annually, ~178 000 undergo thoracentesis. While it is known that malignant pleural effusion portends a poor prognosis, mortality of patients with nonmalignant effusions has not been well studied.This prospective cohort study evaluated 308 patients undergoing thoracentesis. Chart review was(More)
Background. Sepsis is a major cause of morbidity and mortality among older adults. The main goals of this study were to assess the association of sepsis at intensive care unit (ICU) admission with mortality and to identify predictors associated with increased mortality in older adults. Methods. We conducted a prospective cohort study of 309 participants ≥60(More)
We report the case of a 3-year-old girl affected by major thalassemia. She was treated with Deferasirox (DFR), an oral iron chelator, at the dosage of 33 mg/kg per day since the age of 2 years. During the following months, the child underwent three admissions for fever, vomiting, metabolic acidosis, increased azotemia and dehydration. One episode was(More)