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RATIONALE Delirium is a frequent occurrence in older intensive care unit (ICU) patients, but the importance of the duration of delirium in contributing to adverse long-term outcomes is unclear. OBJECTIVES To examine the association of the number of days of ICU delirium with mortality in an older patient population. METHODS We performed a prospective(More)
OBJECTIVE There is a high prevalence of delirium in older medical intensive care unit (ICU) patients and delirium is associated with adverse outcomes. We need to identify modifiable risk factors for delirium, such as medication use, in the ICU. The objective of this study was to examine the impact of benzodiazepine or opioid use on the duration of ICU(More)
IMPORTANCE Little is known about functional trajectories of older persons in the year before and after admission to the intensive care unit (ICU) or how pre-ICU functional trajectories affect post-ICU functional trajectories and death. OBJECTIVES To characterize functional trajectories in the year before and after ICU admission and to evaluate the(More)
RATIONALE Most of the 1.4 million older adults who survive the intensive care unit (ICU) annually in the United States face increased disability, but little is known about those who achieve functional recovery. OBJECTIVES Our objectives were twofold: to evaluate the incidence and time to recovery of premorbid function within 6 months of a critical illness(More)
OBJECTIVES To describe the occurrence of delirium in a cohort of older medical intensive care unit (ICU) patients and its short-term duration in the hospital and to determine the association between preexisting dementia and the occurrence of delirium. DESIGN Prospective cohort study. SETTING Fourteen-bed medical ICU of an 800-bed university teaching(More)
INTRODUCTION Delirium is a serious and prevalent problem in intensive care units (ICU). The purpose of this study was to develop a research algorithm to enhance detection of delirium in critically ill ICU patients using chart review to complement a validated clinical delirium instrument. METHODS Prospective cohort study of 178 patients 60 years and older(More)
BACKGROUND Delirium is a highly prevalent disorder among older patients in the intensive care unit. METHODS We performed a prospective cohort study of 304 patients 60 years or older admitted from September 5, 2002, through September 30, 2004, to a 14-bed ICU in an urban university teaching hospital. The main outcome measure was ICU delirium that developed(More)
OBJECTIVES To compare the Confusion Assessment Method (CAM) and CAM for the Intensive Care Unit (CAM-ICU) methods for detecting delirium in alert, nonintubated older ICU patients. DESIGN Comparison study. SETTING Fourteen-bed medical ICU of an 800-bed university teaching hospital. PARTICIPANTS Twenty-two patients aged 65 and older admitted to the ICU.(More)
INTRODUCTION We assessed smoking data from the Veterans Health Administration (VHA) electronic medical record (EMR) Health Factors dataset. METHODS To assess the validity of the EMR Health Factors smoking data, we first created an algorithm to convert text entries into a 3-category smoking variable (never, former, and current). We compared this EMR(More)
OBJECTIVE With improved survival of HIV-infected persons on antiretroviral therapy and growing prevalence of non-AIDS diseases, we asked whether the VACS Index, a composite measure of HIV-associated and general organ dysfunction predictive of all-cause mortality, predicts hospitalization and medical intensive care unit (MICU) admission. We also asked(More)