Marek Zielinski

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Since atherosclerosis has been proven to be an inflammatory disease, it is obvious that the proper treatment for dyslipidemia should not only correct lipid parameters but also inhibit inflammation. Monocytes and monocyte-derived proinflammatory cytokines are widely known to be involved in the formation and rupture of the atherosclerotic plaque. The aim of(More)
The aim of this study was to evaluate the levels of lipid and extralipid parameters in patients with atherogenic dyslipidemia. We investigated the lipid-lowering therapeutic efficacy of fenofibrate and its extralipid influence on oxidized low-density lipoprotein (oxLDL), C-reactive protein (CRP), Fibrinogen, factor VII and plasminogen activator type 1(More)
The aim of this study was to evaluate levels of lipid and extralipid parameters in patients with atherogenic dyslipidemia. We investigated the lipid-lowering therapeutic efficacy of fenofibrate and its extralipid influence on oxidized low-density lipoprotein (oxLDL), C-reactive protein (CRP), Fibrinogen, factor VII and plasminogen activator type 1 (PAI-1)(More)
Many pharmacological investigations have demonstrated that antidepressant agents profoundly affect serotonergic and noradrenergic neurotransmission. The molecular mechanisms by which these drugs exert their therapeutic action have not been clearly established. In our study, the possibility that antidepressant drug action is associated with dopamine(More)
Nearly all present-day commercial intrusion detection systems are based on a hierarchical architecture. Nodes at the bottom of the hierarchy collect information, which is passed to higher nodes in the hierarchy until the root node is reached. The root node is a command and control system that evaluates attack signatures and issues responses. Many single(More)
The current study evaluates the impact of sewage sludge and urban reservoir sediment on changes in total and Toxic Equivalency (TEQ) PCDD/PCDF concentration in soil and phytotoxicity measured using three test species: Lepidium sativum, Sinapis alba, and Sorghum saccharatum, during 5 weeks of Cucurbita pepo L. cv 'Atena Polka' (zucchini) cultivation. 'Atena(More)
In psychopharmacology of depression, we observe two ways of research. One group is focused on catecholamines action. Second one fixes attention on neuronal morphogenesis and synaptic plasticity. The intimate connection of astro-cytes, neurons and synaptic endings determines glial participation in neural homeostasis. Consequently this situation enlarges the(More)
– The authors present the methods of ECG signal simulation especially ST-Elevation Myocardial Infarction known as STEMI. It occurs in the case of blood flow around and towards heart problem. It is strongly associated with a heart attack due to low level of oxygen transported to the heart muscle. The most common symptoms of this disease are chest pain,(More)
High resolution Time Interval Measurement Systems (TIMS) can be applied in experimental physics, ultrasonic flow meters, distance meters, or clock period meters. In this paper the problem of single-stage, high resolution TIMS design and implementation in programmable CMOS FPGA devices is discussed. Different architectures of TIMS are compared. Moreover,(More)