Learn More
BACKGROUND Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, osteoarthrosis (OA), and healthy control (HC). METHODS PBMCs(More)
Osteoarthritis is an incurable joint disease manifesting itself with gradually progressing degenerative changes, leading to premature motor disability. These changes mainly occur owing to an imbalance between the processes of degeneration and regeneration of articular cartilage structures. Until now many risk factors favoring the development of degenerative(More)
The aim of the study was to assess the results of treating knee osteoarthrosis with total knee arthroplasty (TKA) after previous tibia and/or femur fractures resulting in axial limb deformities. Thirty-six knees (34 patients) were operated on. At the most recent follow-up, 4.8 years after surgery, all but one patient demonstrated an improvement in both(More)
BACKGROUND The aim of the study was to analyze effectiveness and safety of packing the medullary canal of the tibia and femur with Herafill (Heraeus Medical GmbH, Wehrheim, Germany), a void filler and antibiotic carrier, during second stage revision total knee arthroplasty (TKA) for periprosthetic joint infection (PJI). METHODS Two groups were formed of(More)
BACKGROUND Stimulation of bony union by means of various physical modalities has not been widely used in clinical practice. Extracorporeal shock wave therapy (ESWT) offers the most promise. ESWT was first used to crush kidney stones (lithotripsy) in 1980. It is based on a sound rationale. Shock waves penetrate soft tissues and to release mechanical energy(More)
The issue of a stabile, long lasting bone-implant interface is still very valid. One of the new models of uncemented hip prosthesis is the Bicontact prosthesis made by Aesculap. This four-part endoprosthesis offers two types of cups: threaded München type and spherical Plasmacup type. The prosthesis stem is a wedged type stem, porous in the proximal type.(More)
Background. In view of difference of opinion regarding the clinical value of limb lengthening by epiphyseal distraction we decided to analyze our own experiences in this area. Material and methods. Our research involved 31 children, 18 girls and 13 boys ranging in age from 7 to 14 years, treated by means of epiphyseal distraction in 17 femoral and 14 tibial(More)
The purpose of this study was to establish the characteristics at magnetic resonance (MR) imaging of the normal physis of the tibia and of the fibula during development and maturation. Sixty MR imaging studies of the knee were performed in male and female subjects aged 1-20 years who had no clinical symptoms or radiographic abnormality in the lower(More)
BACKGROUND Hip arthroplasty is one of the most frequently performed orthopedic procedures with high scores of success while its most common complication is aseptic loosening of the acetabular component, which may result from host bone loss or even from pelvis discontinuity. The purpose of the study was to evaluate results in patients after revision(More)
PURPOSE The aim of this study was to analyse the results of treatment of sonographically diagnosed type IIb developmental hip dysplasia and to identify residual hip dysplasia using clinical and radiological assessment. METHODS We retrospectively reviewed the data of 49 children (59 type IIb and 39 type I hips, according to Graf's monographic(More)