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BACKGROUND Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, osteoarthrosis (OA), and healthy control (HC). METHODS PBMCs(More)
The aim of the study was to assess the results of treating knee osteoarthrosis with total knee arthroplasty (TKA) after previous tibia and/or femur fractures resulting in axial limb deformities. Thirty-six knees (34 patients) were operated on. At the most recent follow-up, 4.8 years after surgery, all but one patient demonstrated an improvement in both(More)
Osteoarthritis is an incurable joint disease manifesting itself with gradually progressing degenerative changes, leading to premature motor disability. These changes mainly occur owing to an imbalance between the processes of degeneration and regeneration of articular cartilage structures. Until now many risk factors favoring the development of degenerative(More)
BACKGROUND Stimulation of bony union by means of various physical modalities has not been widely used in clinical practice. Extracorporeal shock wave therapy (ESWT) offers the most promise. ESWT was first used to crush kidney stones (lithotripsy) in 1980. It is based on a sound rationale. Shock waves penetrate soft tissues and to release mechanical energy(More)
Background. In view of difference of opinion regarding the clinical value of limb lengthening by epiphyseal distraction we decided to analyze our own experiences in this area. Material and methods. Our research involved 31 children, 18 girls and 13 boys ranging in age from 7 to 14 years, treated by means of epiphyseal distraction in 17 femoral and 14 tibial(More)
The aim of the study was to evaluate the results of the medial patellofemoral ligament reconstruction with a medial strip of patellar tendon autograft after a minimum 2-year followup. Ten patients (10 knees) were operated on by one surgeon, according to the modified technique, described by Camanho, without any bone plug at free graft end. The mean age of(More)
PURPOSE The aim of this study was to analyse the results of treatment of sonographically diagnosed type IIb developmental hip dysplasia and to identify residual hip dysplasia using clinical and radiological assessment. METHODS We retrospectively reviewed the data of 49 children (59 type IIb and 39 type I hips, according to Graf's monographic(More)
PURPOSE Chronic tendinopathy of lateral epicondyle of the humerus, commonly known as "tennis elbow" is one of the most frequent tendinopathies caused by recurrent overload of the muscle origins. The aim of the study was to assess the effectiveness of treating lateral epicondylitis (LE) with autologous conditioned plasma (ACP) and betamethasone injections,(More)
The purpose of this study was to determine the incidence of the leg length discrepancy (LLD) in Legg-Calve-Perthes disease and whether there is any correlation between LLD and age at onset, gender, type of treatment, and severity of disease. The study population consisted of 261 patients with unilateral involvement who had reached skeletal maturity at last(More)
PURPOSE The aim of our study was to find whether an injury of the knee joint tissues increases gene expression of selected hyaline cartilage degenerating enzymes such as matrix metaloproteinases (MMP) and aggreacaneses (Agg). METHODS A total of 138 patients (81 female, 57 male) were admitted for knee arthroscopy with a mean age of 38.8 years. Full blood(More)