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BACKGROUND Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, osteoarthrosis (OA), and healthy control (HC). METHODS PBMCs(More)
BACKGROUND. Despite extensive current knowledge about fractures of the femoral shaft, the choice between antegrade and retrograde intramedullary (IM) nailing with respect to the future function of the joint serving to introduce the nail continues to raise controversy. To compare knee function in patients with a healed fracture of the femoral shaft fixed by(More)
A massive accumulation of inflammatory cells in synovial tissues is a major pathological feature of rheumatoid arthritis (RA). Neutrophiles dominate synovial fluid while rheumatoid synovium is infiltrated with mononuclear cells. Mechanisms regulating influx of particular subpopulations of leukocytes into articular cavity and synovium compartment are not(More)
Background. Despite the significant progress in medicine in recent years, the number of children with cerebral palsy world-wide is growing systematically, often causing treatment problems. The goal of the present study was to evaluate lengthening of the Achilles tendon in the subcutaneous treatment of equines contractures. Material and methods. We analyzed(More)
BACKGROUND Stimulation of bony union by means of various physical modalities has not been widely used in clinical practice. Extracorporeal shock wave therapy (ESWT) offers the most promise. ESWT was first used to crush kidney stones (lithotripsy) in 1980. It is based on a sound rationale. Shock waves penetrate soft tissues and to release mechanical energy(More)
The aim of the study was to retrospectively review results of operative treatment for coverage deficit of femoral head in children with severe epiphysis displacement in Legg-Calvé-Perthes (LCP) disease. The material included 23 shelf acetabuloplasty procedures for LCP disease. The average age at diagnosis was 8.1 years (range 4-12). Mean follow-up was 5.8(More)
Background. This study aimed to assess contact between Recon Shell reinforcement cages used in revision hip arthroplasty and the bony base. Radiographic examinations were performed with the use of multi-energy computed tomography. Material and methods. We tentatively assess the fixation of Burch-Schneider reinforcement cages (Recon Shell made by Aesculap(More)
INTRODUCTION The goal of the reported study was an evaluation of results, obtained in the treatment of knee joints with intraarticular pathologies, concomitant with cysts in the popliteal fossa. We hypothesized that removal of popliteal cyst and associated pathology will provide improvement in function, pain of operated knee and patient satisfaction. (More)
BACKGROUND Osteoarthritis is a serious social problem. Young people usually present with secondary degenerative changes. These patients find it particularly difficult to accept symptoms, as they are at their peak of professional activity and family life. They have high expectations regarding improvement in life comfort. The aim of this study was to analyse(More)
SUMMARY Background. Cerebrally palsied children demonstrated limited independence while performing various activities of daily living, which is due to disorders of postural control. The best solution to improve postural con trol is the use of therapies that simultaneously focus on the sense of balance and motor skills. Such possibilities for patients with(More)