Marek Schmidt

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Background: It is well recognized that the presence of positive surgical margins (PSM) after radical prostatectomy (RP) adversely affects cancer specific outcomes and recent evidence from randomized trials supports the use of adjuvant radiotherapy in these cases. However, not all of the patients with PSM develop disease recurrence and the policy of adjuvant(More)
The receptor for advanced glycation end products (RAGE) and its ligands are involved in the pathogenesis of cancer. Glyoxalase I (GLO1) is an enzyme which detoxifies advanced glycation end product (AGE) precursors. The aim of the study was to find out the relationship between four polymorphisms (single nucleotide polymorphism, SNP) of the RAGE gene (AGER)(More)
Automatic Term Recognition focuses on the extraction of words and multi-word expressions that are significant for a given domain. There is a considerable interest in using ATR for automatic metadata generation, creation of thesauri and terminological glossaries, keyword extraction, ontology building, etc. In this paper, we build upon the work done at the(More)
Contemporary tools estimating increased risk of prostate cancer (PCa) relapse after radical prostatectomy (RP) are far from perfect and there has been an intensive search for additional predictive variables. We aimed to explore whether the parameters of postoperative ultrasensitive prostate-specific antigen (PSA) decline provide additional information for(More)
OBJECTIVE To evaluate the prognostic significance of symptoms related to renal cell carcinoma (RCC) in comparison with incidentally detected tumours in a group of long-term observed patients. MATERIAL AND METHODS The study included 396 patients operated for RCC between 1982 and 2001. The patients were classified according to age, gender, detection mode,(More)
This paper deals with information extraction technologies supporting semantic annotation and logical organization of textual content in semantic wikis. We describe our work in the context of the KiWi project which aims at developing a new knowledge management system motivated by the wiki way of collaborative content creation that is enhanced by the semantic(More)
This paper deals with key functionalities of the KiWi annotation component and shows how it enables seamless combination of informal and formal knowledge and transformation of the former to the latter. It demonstrates how the advanced KiWi features, such as nested content items, reasoning and information extraction, can be used together to make rich(More)
INTRODUCTION Greater acceptance of sexual minorities has enabled people with transsexualism access to adequate treatment and social integration. Gender reassignment surgery is a complex phase in the care of transsexual patients. In response to a greater volume of patients, surgical techniques have evolved and the outcome in patients with male-to-female(More)
OBJECTIVE The aim of this study was to construct a stratification model based on early postoperative kinetics of prostate-specific antigen (PSA) to select the most suitable high-risk patients for early intervention after radical prostatectomy (RP). MATERIALS AND METHODS The study evaluated 205 men who had undergone RP without any adjuvant treatment. All(More)
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