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Experimental results obtained from studies on Goldblatt rats and spontaneously hypertensive rats as well as theoretical considerations render possible an approximate analysis and evaluation of the relative significance of specific factors at different levels of the heart for the manifestation of cardiac failure under chronic pressure overload. In our(More)
Micro, small and medium-sized enterprises (SME) are socially and economically important, since they represent 99 % of all enterprises in the European Union (EU). They provide around 65 million jobs and contribute to entrepreneurship and innovation. Being an essential ingredient of presentday business, information technology (IT) on one hand works as an(More)
ICT Governance’s principles and its associated frameworks and methodologies are important approaches to deriving organizational value from ICT investments. Achieving strategic alignment is a major governance concern in both the private and public sectors, but many of the private sector’s, financially focused evaluation methodologies are less useful in the(More)
The end-systolic and end-diastolic pressure-volume or stress-length curves define the margins of the various conceivable courses of pressure-volume or stress-length loops. Although the end-systolic pressure-volume and stress-length relations of isovolumetric and afterloaded contractions are not entirely identical, the area between isovolumetric maxima- and(More)
The functional significance of alterations in contractile proteins was investigated in the chronically overloaded left ventricle of Goldblatt rats and spontaneously hypertensive rats (SHRs). Congestive cardiac insufficiency occurring in late stages of pressure overload is associated with impaired contractility, as well as significant structural dilatation.(More)
Mechanical and energetic consequences of myocardial transformation and of ventricular configuration on the other were separately analysed. The considerations were realized on representative samples of normotensive rats and spontaneously hypertensive rats (SHR) in compensated stages, as well as in SHR in a state of congestive cardiac failure. Cardiac dynamic(More)
The significance of various factors for the development of structural dilatation in the chronically pressure-loaded and failing heart were evaluated. The investigations were performed on male rats with renal (Goldblatt II) and spontaneous (Aoki-Okamoto) hypertension at different stages of haemodynamic overload. Two groups of SHR were submitted to(More)
In previous studies swimming training (ST) of spontaneously hypertensive rats (SHR) at 36 degrees water temperature (WT) led to a decrease in blood pressure (BP). A similar effect of ST has not been described in human hypertension. Our purpose was to investigate the influence of WT on this training effect, the influence of ST on LV hypertrophy and the(More)
Today’s society is exposed to an increasing number of disasters and large scale emergencies (e.g. earthquake in Haiti, global swine flu, or manmade disasters like the oil spill in the Gulf of Mexico). Information and communication technology (ICT) can help to prevent and mitigate the effects of threatening situations if applied appropriately. In industry(More)