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  • Adriana Gibara Guimarães, Luciana Scotti, +7 authors Lucindo José Quintans Júnior
  • Medicine, Chemistry
  • Life sciences
  • 2014 (First Publication: 22 October 2014)
  • AIMS The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice. MAIN METHODS Carvacrol treatment (12.5-50mg/kgs.c.) once dailyExpand
  • Makson G. B. Oliveira, Renan Guedes de Brito, +13 authors Lucindo José Quintans-Júnior
  • Medicine, Chemistry
  • Chemico-biological interactions
  • 2016 (First Publication: 25 July 2016)
  • The anti-hyperalgesic effect of the complex containing α-terpineol (αTPN) and β-cyclodextrin (βCD) was analyzed in a non-inflammatory chronic muscle pain model, as well as its mechanism of actionExpand
  • Daniele Nascimento Gouveia, Janara Santos Costa, +11 authors Adriana Gibara Guimarães
  • Medicine, Biology
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 2018 (First Publication: 1 September 2018)
  • α-Terpineol (TP) is present in a wide range of essential oils of the genus Eucalyptus, with recognized potential for a range of biological effects, such as analgesic. Hence, our study aimed toExpand
  • Alejandro Speck Planche, Marcus Tullius Scotti, América García López, Vicente Paulo Emerenciano, Enrique Molina Pérez, Eugenio Uriarte
  • Medicine, Chemistry
  • Molecular Diversity
  • 2009 (First Publication: 2 April 2009)
  • The increasing resistance of Mycobacterium tuberculosis to the existing drugs has alarmed the worldwide scientific community. In an attempt to overcome this problem, two models for the design andExpand
  • Luciana Scotti, Francisco Jaime Bezerra Mendonça Junior, Diogo Rodrigo Magalhaes Moreira, Marcelo da Silva, Ivan da R. Pitta, Marcus Tullius Scotti
  • Medicine, Chemistry
  • Current topics in medicinal chemistry
  • 2012 (First Publication: 29 January 2013)
  • Flavonoids are phenolic compounds, secondary metabolites of plants that cause several benefits to our health, including helping the treatment against cancer. These pharmacological properties areExpand
  • Klinger Antonio da Franca Rodrigues, Cínthia Nóbrega de Sousa Dias, +14 authors Márcia Rosa de Oliveira
  • Medicine, Chemistry
  • European journal of medicinal chemistry
  • 2015 (First Publication: 1 December 2015)
  • This study evaluated the effects of 2-amino-thiophene derivatives on the promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and their possible mechanisms of action. Initially,Expand
  • Mariane B. Fernandes, Marcus Tullius Scotti, Marcelo José Pena Ferreira, Vicente de Paulo Emerenciano
  • Medicine, Chemistry
  • European journal of medicinal chemistry
  • 2008 (First Publication: 1 October 2008)
  • Some sesquiterpene lactones (SLs) are the active compounds of a great number of traditionally medicinal plants from the Asteraceae family and possess considerable cytotoxic activity. Several studiesExpand