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The cochlear place-frequency map of the adult and developing mongolian gerbil
TLDR
The place-frequency map of the gerbil was determined by iontophoretic application of horseradish peroxidase in physiologically characterized single auditory nerve fibers from a '3-dimensional' reconstruction of the cochleae. Expand
A physiological place–frequency map of the cochlea in the CBA/J mouse
TLDR
The simple logarithmic place-frequency relation found in the mouse indicates that mice are acoustic generalists rather than specialists. Expand
Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss
TLDR
A lack of the TrkB receptor and its ligand, the neurotrophin brain-derived neurotrophic factor (Bdnf), in the late postnatal or adult cochlea using mouse mutants indicates a substantial potential for re-innervation processes in the mature coChlea, which may be of relevance for treatment of hearing loss in humans. Expand
Relationship between tone burst discharge pattern and spontaneous firing rate of auditory nerve fibres in the guinea pig
TLDR
The response of single auditory nerve fibres in the guinea pig to tone bursts was carried out and the ratio of onset-to-adapted firing rate tended to decrease with increasing stimulus intensity in both low and high CF fibres with low spontaneous firing rates. Expand
A physiological frequency-position map of the chinchilla cochlea
TLDR
The findings affirm that frequency-position maps in the mammalian cochlea depend on the condition of the inner ear, and substantiate the notion that "crowding" at lower frequencies appears to be a specialization rather than a general feature. Expand
Auditory nerve fibre responses to salicylate revisited
TLDR
The altered response properties can be interpreted by the known effects of salicylate on the prestin mediated active process of the outer hair cells and cannot be caused by cochlear nerve hyperactivity. Expand
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss.
TLDR
Hearing loss was linked to a loss of the KCNQ4 potassium channel in membranes of OHCs in the basal and midbasal cochlear turn, preceding hair cell degeneration and leading to a similar phenotype as elicited by pharmacologic blockade of KCNZ4 channels. Expand
Structure and function of the cochlea in the African mole rat (Cryptomys hottentotus): evidence for a low frequency acoustic fovea
TLDR
It is speculated that in Cryptomys hottentotus an acoustic fovea is present in the frequency range between 0.6 and 1 kHz, in analogy to echolocating bats, about half of the cochlea is devoted to the analysis of a narrow frequency band within the hearing range. Expand
Shapes of rate-versus-level functions of primary auditory nerve fibres: Test of the basilar membrane mechanical hypothesis
TLDR
It was found that, within the limits of reliability of the curve fitting procedure, the breakpoint position was the same in fibres from the same CF regions in any given animal, consistent with the notion that the breakpoints are determined by global basilar membrane mechanics and not by processes private to each nerve fibre. Expand
Water channel proteins in the inner ear and their link to hearing impairment and deafness.
TLDR
The currently available knowledge regarding the expression and function of AQPs in the inner ear is presented and special consideration is given to AQP subtypes AQP2, AQP4 and AQP5, which have been studied most extensively. Expand
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