Marco Salvatore

Suggest Changes
Arturo Brunetti43
Bruno Alfano30
Sabina Pappatà25
Mario Quarantelli25
Raffaele Liuzzi16
43Arturo Brunetti
36Sabina Pappatà
32Bruno Alfano
27Mario Quarantelli
20Paolo Barone

Filter Results:

Publication Year

1975
2017

Publication Type

Co-author

Publication Venue

Brain Region

Cell Type

Key Phrases

Method

Organism

Learn More
Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction.
UNLABELLED We present software for integrated analysis of brain PET studies and coregistered segmented MRI that couples a module for automated placement of regions of interest (ROI) with 4 alternative methods for partial-volume-effect correction (PVEc). The accuracy and precision of these methods have been measured using 4 simulated (18)F-FDG PET studies… (More)
Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis.
A fully automated magnetic resonance (MR) segmentation method for identification and volume measurement of demyelinated white matter has been developed. Spin-echo MR brain scans were performed in 38 patients with multiple sclerosis (MS) and in 46 healthy subjects. Segmentation of normal tissues and white matter lesions (WML) was obtained, based on their… (More)
Grey matter loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study.
Global grey matter (GM) loss has been reported in multiple sclerosis (MS). We addressed the question of if and where GM loss is localized by means of optimized voxel-based morphometry, applied to MRI studies of 51 patients with clinically defined relapsing-remitting MS and 34 age-matched normal subjects, segmented into normal and abnormal brain tissues… (More)
Anxiety is associated with striatal dopamine transporter availability in newly diagnosed untreated Parkinson's disease patients.
BACKGROUND Anxiety is a common non-motor symptom among patients with Parkinson's disease (PD). Although the etiology of anxiety in PD is likely to be multifactorial, a dysfunction in the dopaminergic system might be implicated in its pathogenesis. The aim of our study was to investigate a possible dopaminergic mechanism involved in anxiety in newly… (More)
An MRI digital brain phantom for validation of segmentation methods
Knowledge of the exact spatial distribution of brain tissues in images acquired by magnetic resonance imaging (MRI) is necessary to measure and compare the performance of segmentation algorithms. Currently available physical phantoms do not satisfy this requirement. State-of-the-art digital brain phantoms also fall short because they do not handle… (More)
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses.
Iodine-123 labelled iomazenil (IMZ) is a specific tracer for the GABAA receptor, the dominant inhibitory synapse of the brain. The cerebral distribution volume (Vd) of IMZ may be taken as a quantitative measure of these synapses in Alzheimer's disease (AD), where synaptic loss tends indiscriminately to affect all cortical neurons, albeit more so in some… (More)
Multiparametric display of spin-echo data from MR studies of brain.
A magnetic resonance (MR) image processing technique that uses a single color image for simultaneous presentation of spin-echo information and its application to MR studies of the brain is described. Relaxation rate and proton-density maps were calculated from 160 brain MR studies performed at 1.5 and 1.0 T with standard spin-echo sequences. Maps were fused… (More)
Simultaneous display of multiple MR parameters with "quantitative magnetic color imaging".
A new technique for simultaneous display of multiple MR parameters with a single color-coded image is described. The method is based on the multiparametric nature of MR signals and benefits from the physiologic ability to discriminate color levels better than gray levels. The T1 and T2 relaxation rate maps are first obtained from multi-echo SE and partial… (More)
Repeatability, Reproducibility and Standardisation of a Laser Doppler Imaging Technique for the Evaluation of Normal Mouse Hindlimb Perfusion
BACKGROUND Preclinical perfusion studies are useful for the improvement of diagnosis and therapy in dermatologic, cardiovascular and rheumatic human diseases. The Laser Doppler Perfusion Imaging (LDPI) technique has been used to evaluate superficial alterations of the skin microcirculation in surgically induced murine hindlimb ischemia. We assessed the… (More)
Brain atrophy and lesion load in a large population of patients with multiple sclerosis.
OBJECTIVE To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. METHODS The study population consisted of 597 patients with MS and 104 control subjects. The MRI parameters were abnormal WM… (More)