Marco Pierini

  • Citations Per Year
Learn More
The main purpose of this work is the development and validation of a general scheme based on a systematic and automatic “quasi-flexible” docking approach for studying stereoselective recognition mechanisms. To achieve our goals we explore the conformational and configurational space for smallor medium-size flexible molecules in a systematic way, seeking a(More)
Three brush-type chiral stationary phases (CSPs) differing in the particle size of the starting silica particles have been prepared by covalent grafting of the pi-acidic bis-(3,5-dinitrobenzoyl)-derivative of trans-1,2-diaminocyclohexane (DACH-DNB). Starting silica particles of 4.3, 2.6 and 1.9micron were used to generate the final CSPs using an improved,(More)
The present article analyses the current situation of End-of-Life-of-Vehicles (ELVs) management in Europe, with particular attention on Italian condition. Similarly to other European countries, metal recycling is the main activity of the whole system, but such situation is evolving due to the 2000/53/EC Directive, which sets out targets for Reuse, Recycling(More)
OBJECTIVES Powered 2-wheelers (PTWs) are becoming increasingly popular in Europe. They have the ability to get around traffic queues, thus lowering fuel consumption and increasing mobility. The risk of rider injury in a traffic crash is however much higher than that associated with car users. The European project, Powered Two Wheeler Integrated Safety(More)
The structure, stability, and reactivity of proton-bound diastereomeric [M x H x A]+ complexes between some amino acid derivatives (A) and several chiral tetra-amide macrocycles (M) have been investigated in the gas phase by ESI-FT-ICR and ESI-ITMS-CID mass spectrometry. The displacement of the A guest from the diastereomeric [M x H x A]+ complexes by(More)
OBJECTIVE The aim of this study was to assess the feasibility and quantitative potential benefits of a motorcycle autonomous emergency braking (MAEB) system in fatal rear-end crashes. A further aim was to identify possible criticalities of this safety system in the field of powered 2-wheelers (PTWs; e.g., any additional risk introduced by the system(More)
We developed a cryo-HPLC/UV method for the simultaneous determination of artemisinin (1), alpha-dihydroartemisinin (2alpha), beta-dihydroartemisinin (2beta), and a ubiquitous thermal decomposition product of 2 (designated as diketoaldehyde, 3), starting from the International Pharmacopoeia monograph on dihydroartemisinin. The method takes for the first time(More)
OBJECTIVE In 2006, Motorcycle Autonomous Emergency Braking (MAEB) was developed by a European Consortium (Powered Two Wheeler Integrated Safety, PISa) as a crash severity countermeasure for riders. This system can detect an obstacle through sensors in the front of the motorcycle and brakes automatically to achieve a 0.3 g deceleration if the collision is(More)
A tailored model for the assessment of environmental benefits achievable by light-weighting design solutions in the automotive field is presented. The model is based on the Fuel Reduction Value (FRV) coefficient which expresses the Fuel Consumption (FC) saving involved by a 100 kg vehicle mass reduction. The work is composed by two main sections: simulation(More)
In the last decade European accidentology data, divided per mode of transport, have shown the increasing relevance of safety for Vulnerable Road User (VRU). In particular Powered Two-Wheeler (PTW) accidents are increasing both as number of events and as percentage of the total fatalities. The European Community has promoted and co-financed several research(More)