Marco Mossa

Learn More
Alport syndrome (AS) is a genetic disease of type IV collagen involving non-homogeneous patterns of inheritance characterized clinically by the presence of progressive haematuric nephritis leading to end-stage renal disease (ESRD), hearing loss and/or ophthalmologic abnormalities. The aim of this study was to investigate, in a cohort of AS patients who had(More)
OBJECTIVES To evaluate the effects of introducing routine ultrasonic screening for the identification and elective surgical treatment of abdominal aortic aneurysms (AAA) at high risk of rupture in the U.K. population of men aged 65-74 years. DESIGN A computer assisted simulation of an AAA screening programme. The simulation incorporated assumptions(More)
Renal transplantation has become an effective form of treatment for end-stage renal failure. Unfortunately, as a consequence of immunological and nonimmunological pathogenic mechanisms, chronic allograft nephropathy is responsible for the loss of a large proportion of kidney grafts after several years and return to dialysis. We have reported herein our 24(More)
The effects of cigarette smoking on male reproduction were studied through measuring the serum estradiol (E2), prolactin (PRL), and total testosterone (T). Smoking men had higher levels of E2 and PRL but normal T compared to nonsmokers. Raised E2 and PRL may be among the mechanisms through which cigarette smoking impairs male reproduction.
Controversy exists as to whether exercise in patients with intermittent claudication causes a harmful biochemical effect associated with an ischaemia-reperfusion injury of skeletal muscle. We report on exercise-induced changes in neutrophil activation, soluble P-selectin and von Willebrand factor in 34 patients with intermittent claudication and 12 matched(More)
A 32-year-old lady presented postnatally with headaches, blurred vision and left leg numbness, which was initially diagnosed as migraine with sciatica. Subsequently, she developed seizures and was admitted to ITU. Investigations revealed abnormal grey matter perfusion in the right occipital region of the brain, multiple lung nodules, lesions in the liver(More)
A group of 42 sensitized dialysis patients showing high reactivity (81%-100%) against a random panel of peripheral blood lymphocytes (PBL), were analyzed for the presence of autoreactive lymphocytotoxic antibodies. The test was performed at different temperatures (4 degrees C, 22 degrees C, 37 degrees C) with dithiothreitol (DTT) against autologous PBL,(More)
Microchimerism is a phenomenon which occurs in some recipients after kidney transplantation (KT) and has been considered to play an important role to the induction or maintenance of allograft tolerance. In order to study the relevance of microchimerism to the long-term outcome of renal allograft (RA), we retrospectively analyzed the presence of(More)
  • 1