Marco L. H. Gruwel

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PURPOSE The purpose of the current study was to use diffusion tensor imaging (DTI) to conduct tractography of the optic radiations (OR) and its component bundles and to assess both the degree of hemispheric asymmetry and the inter-subject variability of Meyer's Loop (ML). We hypothesized that there are significant left versus right differences in the(More)
A common problem in simulations of MRI-experiments based on the numerical solution of the Bloch equations is the finite number of isochromats used in the calculations. This usually results in false or spurious signals and is a source of various differences between calculated and experimentally obtained data. In this paper, we are proposing a technique(More)
So far, the hydrated part of the HPMC matrix has commonly been denoted as a “gel” or “pseudogel” layer. No MRI-based results have been published regarding observation of internal phenomena related to drug dissolution inside swelling polymeric matrices during hydration. The purpose of the study was to detect such phenomena. Multiparametric, spatially and(More)
To resolve contradictions found in morphology of hydrating hydroxypropylmethyl cellulose (HPMC) matrix as studied using Magnetic Resonance Imaging (MRI) techniques. Until now, two approaches were used in the literature: either two or three regions that differ in physicochemical properties were identified. Multiparametric, spatially and temporally resolved(More)
MR images are affected by system delays and gradient field imperfections which induce discrepancies between prescribed and actual k-space trajectories. This could be even more critical for non-Cartesian data acquisitions where even a small deviation from the assumed k-space trajectory results in severe image degradation and artifacts. Knowledge of the(More)
PURPOSE To: 1) Present fornix tractography in its entirety for 20 healthy individuals to assess variability. 2) Provide individual and groupwise whole tract diffusion parameter symmetry assessments prior to clinical application. 3) Compare whole tract diffusion parameter assessments with tract-based spatial statistics (TBSS). MATERIALS AND METHODS(More)
PURPOSE To determine if differences exist between control and diabetic rats in functional magnetic resonance imaging (fMRI) activity of the spinal cord and if fMRI can provide a means of early detection of diabetic neuropathy. MATERIALS AND METHODS fMRI of the spinal cord, using noxious electrical stimulation (15 V ( approximately 8 mA), 0.3 msec, 3 Hz)(More)
Magnetic field gradients play a fundamental role in MR imaging and localized spectroscopy. The MRI experiment, in particular fast MRI, relies on precise gradient switching, which has become more demanding with the constantly growing number of fast imaging techniques. Here we present a simple MR method to measure the behavior of a magnetic field gradient(More)
Acoustic noise produced during single point imaging (SPI) experiments was modulated by changes in the spatial encoding gradients. Parameters of both linear and sine-shaped gradient ramps were modified to minimize the acoustic noise levels. Acoustic noise measurements during SPI were measured on three different gradient systems and revealed that for small(More)
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