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Apathy is a salient feature of various neuropsychiatric disorders, from depression to Alzheimer's disease. We formally assess its prevalence in idiopathic Parkinson's disease (PD) together with its clinical, neuropsychological, and morphometric correlates. Thirty patients with PD and 25 normal controls were assessed using an extensive neuropsychological(More)
This paper presents an experimental evaluation of different features for use in speaker identification. The features are tested using speech data provided by the chains corpus, in a closed-set speaker identification task. The main objective of the paper is to present a novel parametrization of speech that is based on the AM-FM representation of the speech(More)
BACKGROUND Anorexia nervosa commonly arises during adolescence and is associated with more than one medical morbidity. Abnormalities in brain structure (defined as "pseudoatrophy") are common in adolescents with anorexia nervosa; however, their correlations with endocrinological profiles and clinical parameters are still unclear. In particular, no study has(More)
We evaluated the relationship between 11C-methionine PET (11C-METH PET) findings and molecular biomarkers in patients with supratentorial glioma who underwent surgery. A consecutive series of 109 patients with pathologically proven glioma (64 men, 45 women; median age 43 years) referred to our Institution from March 2012 to January 2015 for tumour resection(More)
The recent literature on anorexia nervosa (AN) suggests that functional and structural abnormalities of cortico-limbic areas might play a role in the evolution of the disease. We explored global and regional brain volumes in a cross-sectional and follow-up study on adolescents affected by AN. Eleven adolescents with AN underwent a voxel-based morphometry(More)
BACKGROUND Hunter disease is a rare X-linked mucopolysaccharidosis. Despite frequent neurological involvement, characterizing the severe phenotype, neuroimaging studies are scarce. OBJECTIVES To determine frequency and severity of neuroradiological mucopolysaccharidosis-related features; to correlate them with clinical phenotype; to evaluate their natural(More)
BACKGROUND Subthalamic Deep Brain Stimulation is a valid surgical procedure for the treatment of idiopathic PD, although its precise mechanism of action is still unclear; moreover, there are no conclusive data about the functional anatomy of the human subthalamic region. Identifying the location of active contacts for StnDBS can yield interesting insights(More)
The vast amount of music available electronically presents considerable challenges for information retrieval. There is a need to annotate music items with descriptors in order to facilitate retrieval. In this paper we present a process for determining the music genre of an item using a new set of descriptors. A Wavelet Packet Transform is applied to obtain(More)
Automatic annotation of music files is a key problem in multimedia information retrieval. In this paper we present a solution to this problem that addresses the issues of feature extraction, feature selection and design of classi-fier. We outline a process for feature extraction based on the discrete wavelet packet transform and we evaluate a variety of(More)